A personalized mechanical ventilation approach for patients with adult respiratory distress
syndrome (ARDS) based on lung physiology and morphology, ARDS etiology, lung imaging …

Assessing respiratory mechanics and muscle function is critical for both clinical practice and
research purposes. Several methodological developments over the past two decades have …

Background The effect of personalised mechanical ventilation on clinical outcomes in
patients with acute respiratory distress syndrome (ARDS) remains uncertain and needs to …

Mechanical ventilation is the most used short-term life support technique worldwide and is
applied daily for a diverse spectrum of indications, from scheduled surgical procedures to …

Rationale: High-flow nasal cannula (HFNC) improves the clinical outcomes of nonintubated
patients with acute hypoxemic respiratory failure (AHRF). Objectives: To assess the effects of …

Neural respiratory drive, ie, the activity of respiratory centres controlling breathing, is an
overlooked physiologic variable which affects the pathophysiology and the clinical outcome …

Ventilation is inherently a dynamic process. The present-day clinical practice of
concentrating on the static inflation characteristics of the individual tidal cycle (plateau …

Mechanical ventilation may have adverse effects on both the lung and the diaphragm. Injury
to the lung is mediated by excessive mechanical stress and strain, whereas the diaphragm …

Patients with severe lung injury usually have a high respiratory drive, resulting in intense
inspiratory effort that may even worsen lung damage by several mechanisms gathered …

The adverse effects of mechanical ventilation in acute respiratory distress syndrome (ARDS)
arise from two main causes: unphysiological increases of transpulmonary pressure and …