Mendelian randomization: concepts and scope
RC Richmond, GD Smith - Cold Spring …, 2022 - perspectivesinmedicine.cshlp.org
Mendelian randomization (MR) is a method of studying the causal effects of modifiable
exposures (ie, potential risk factors) on health, social, and economic outcomes using genetic …
exposures (ie, potential risk factors) on health, social, and economic outcomes using genetic …
Mendelian randomization: genetic anchors for causal inference in epidemiological studies
Observational epidemiological studies are prone to confounding, reverse causation and
various biases and have generated findings that have proved to be unreliable indicators of …
various biases and have generated findings that have proved to be unreliable indicators of …
Strengthening the reporting of observational studies in epidemiology using mendelian randomisation (STROBE-MR): explanation and elaboration
Mendelian randomisation (MR) studies allow a better understanding of the causal effects of
modifiable exposures on health outcomes, but the published evidence is often hampered by …
modifiable exposures on health outcomes, but the published evidence is often hampered by …
Skeletal and extraskeletal actions of vitamin D: current evidence and outstanding questions
R Bouillon, C Marcocci, G Carmeliet, D Bikle… - Endocrine …, 2019 - academic.oup.com
The etiology of endemic rickets was discovered a century ago. Vitamin D is the precursor of
25-hydroxyvitamin D and other metabolites, including 1, 25 (OH) 2D, the ligand for the …
25-hydroxyvitamin D and other metabolites, including 1, 25 (OH) 2D, the ligand for the …
Potential drug targets for multiple sclerosis identified through Mendelian randomization analysis
J Lin, J Zhou, Y Xu - Brain, 2023 - academic.oup.com
Multiple sclerosis is a complex autoimmune disease, and several therapies for multiple
sclerosis have been developed and widely used. However, existing medications for multiple …
sclerosis have been developed and widely used. However, existing medications for multiple …
Obesity and vitamin D deficiency: a systematic review and meta‐analysis
M Pereira‐Santos, PRF Costa, AMO Assis… - Obesity …, 2015 - Wiley Online Library
Over the past decade, there have been an increasing number of studies on the association
between vitamin D deficiency and anthropometric state. However, we did not identify any …
between vitamin D deficiency and anthropometric state. However, we did not identify any …
The importance of vitamin d metabolism as a potential prophylactic, immunoregulatory and neuroprotective treatment for COVID-19
Y Xu, DJ Baylink, CS Chen, ME Reeves, J **ao… - Journal of translational …, 2020 - Springer
Abstract The coronavirus disease 2019 (COVID-19) pandemic has led to a declaration of a
Public Health Emergency of International Concern by the World Health Organization. As of …
Public Health Emergency of International Concern by the World Health Organization. As of …
Metabolic syndrome and sarcopenia
H Nishikawa, A Asai, S Fukunishi, S Nishiguchi… - Nutrients, 2021 - mdpi.com
Skeletal muscle is a major organ of insulin-induced glucose metabolism. In addition, loss of
muscle mass is closely linked to insulin resistance (IR) and metabolic syndrome (Met-S) …
muscle mass is closely linked to insulin resistance (IR) and metabolic syndrome (Met-S) …
Vitamin D supplementation for women during pregnancy
LM De‐Regil, C Palacios, LK Lombardo… - Cochrane database …, 2016 - cochranelibrary.com
Background Vitamin D deficiency or insufficiency is thought to be common among pregnant
women. Vitamin D supplementation during pregnancy has been suggested as an …
women. Vitamin D supplementation during pregnancy has been suggested as an …
Vitamin D and obesity: current evidence and controversies
I Karampela, A Sakelliou, N Vallianou… - Current obesity …, 2021 - Springer
Abstract Purpose of Review Evidence from observational studies suggests that obesity is
associated with low vitamin D. As both obesity and hypovitaminosis D present an alarmingly …
associated with low vitamin D. As both obesity and hypovitaminosis D present an alarmingly …