Mendelian randomization: concepts and scope
RC Richmond, GD Smith - Cold Spring …, 2022 - perspectivesinmedicine.cshlp.org
Mendelian randomization (MR) is a method of studying the causal effects of modifiable
exposures (ie, potential risk factors) on health, social, and economic outcomes using genetic …
exposures (ie, potential risk factors) on health, social, and economic outcomes using genetic …
Skeletal and extraskeletal actions of vitamin D: current evidence and outstanding questions
R Bouillon, C Marcocci, G Carmeliet, D Bikle… - Endocrine …, 2019 - academic.oup.com
The etiology of endemic rickets was discovered a century ago. Vitamin D is the precursor of
25-hydroxyvitamin D and other metabolites, including 1, 25 (OH) 2D, the ligand for the …
25-hydroxyvitamin D and other metabolites, including 1, 25 (OH) 2D, the ligand for the …
Strengthening the reporting of observational studies in epidemiology using mendelian randomisation (STROBE-MR): explanation and elaboration
VW Skrivankova, RC Richmond, BAR Woolf… - bmj, 2021 - bmj.com
Mendelian randomisation (MR) studies allow a better understanding of the causal effects of
modifiable exposures on health outcomes, but the published evidence is often hampered by …
modifiable exposures on health outcomes, but the published evidence is often hampered by …
Potential drug targets for multiple sclerosis identified through Mendelian randomization analysis
J Lin, J Zhou, Y Xu - Brain, 2023 - academic.oup.com
Multiple sclerosis is a complex autoimmune disease, and several therapies for multiple
sclerosis have been developed and widely used. However, existing medications for multiple …
sclerosis have been developed and widely used. However, existing medications for multiple …
Metabolic syndrome and sarcopenia
H Nishikawa, A Asai, S Fukunishi, S Nishiguchi… - Nutrients, 2021 - mdpi.com
Skeletal muscle is a major organ of insulin-induced glucose metabolism. In addition, loss of
muscle mass is closely linked to insulin resistance (IR) and metabolic syndrome (Met-S) …
muscle mass is closely linked to insulin resistance (IR) and metabolic syndrome (Met-S) …
The importance of vitamin d metabolism as a potential prophylactic, immunoregulatory and neuroprotective treatment for COVID-19
Y Xu, DJ Baylink, CS Chen, ME Reeves, J **ao… - Journal of translational …, 2020 - Springer
Abstract The coronavirus disease 2019 (COVID-19) pandemic has led to a declaration of a
Public Health Emergency of International Concern by the World Health Organization. As of …
Public Health Emergency of International Concern by the World Health Organization. As of …
Vitamin D and obesity: current evidence and controversies
I Karampela, A Sakelliou, N Vallianou… - Current obesity …, 2021 - Springer
Abstract Purpose of Review Evidence from observational studies suggests that obesity is
associated with low vitamin D. As both obesity and hypovitaminosis D present an alarmingly …
associated with low vitamin D. As both obesity and hypovitaminosis D present an alarmingly …
Definition, assessment, and management of vitamin D inadequacy: suggestions, recommendations, and warnings from the Italian Society for Osteoporosis, Mineral …
F Bertoldo, L Cianferotti, M Di Monaco, A Falchetti… - Nutrients, 2022 - mdpi.com
In the recent years, both the prescriptions of serum 25 (OH) D levels assay, and vitamin D
supplementation are constantly increasing, as well as the costs to be incurred relating to …
supplementation are constantly increasing, as well as the costs to be incurred relating to …
Vitamin D deficiency: defining, prevalence, causes, and strategies of addressing
KD Cashman - Calcified tissue international, 2020 - Springer
There are variable definitions of vitamin D deficiency, based on different thresholds of serum
25-hydroxyvitamin D (25 (OH) D); this has a major bearing on the prevalence estimates of …
25-hydroxyvitamin D (25 (OH) D); this has a major bearing on the prevalence estimates of …
Rationale and plan for vitamin D food fortification: a review and guidance paper
S Pilz, W März, KD Cashman, ME Kiely… - Frontiers in …, 2018 - frontiersin.org
Vitamin D deficiency can lead to musculoskeletal diseases such as rickets and
osteomalacia, but vitamin D supplementation may also prevent extraskeletal diseases such …
osteomalacia, but vitamin D supplementation may also prevent extraskeletal diseases such …