Advances in mass spectrometry imaging for spatial cancer metabolomics

X Ma, FM Fernández - Mass spectrometry reviews, 2024 - Wiley Online Library
Mass spectrometry (MS) has become a central technique in cancer research. The ability to
analyze various types of biomolecules in complex biological matrices makes it well suited for …

Advances in mass spectrometry-based metabolomics for investigation of metabolites

JL Ren, AH Zhang, L Kong, XJ Wang - RSC advances, 2018 - pubs.rsc.org
Metabolomics is the systematic study of all the metabolites present within a biological
system, which consists of a mass of molecules, having a variety of physical and chemical …

Atmospheric pressure MALDI mass spectrometry imaging of tissues and cells at 1.4-μm lateral resolution

M Kompauer, S Heiles, B Spengler - Nature methods, 2017 - nature.com
We report an atmospheric pressure (AP) matrix-assisted laser desorption/ionization (MALDI)
mass spectrometry imaging (MSI) setup with a lateral resolution of 1.4 μm, a mass resolution …

Nondestructive tissue analysis for ex vivo and in vivo cancer diagnosis using a handheld mass spectrometry system

J Zhang, J Rector, JQ Lin, JH Young, M Sans… - Science translational …, 2017 - science.org
Conventional methods for histopathologic tissue diagnosis are labor-and time-intensive and
can delay decision-making during diagnostic and therapeutic procedures. We report the …

Analysis of tissue specimens by matrix-assisted laser desorption/ionization imaging mass spectrometry in biological and clinical research

JL Norris, RM Caprioli - Chemical reviews, 2013 - ACS Publications
Human beings are adept at discerning relevant information from complex systems by
processing visual information. Similarly, as scientists labor to understand the fundamental …

Advances in MALDI mass spectrometry imaging single cell and tissues

X Zhu, T Xu, C Peng, S Wu - Frontiers in Chemistry, 2022 - frontiersin.org
Compared with conventional optical microscopy techniques, mass spectrometry imaging
(MSI) or imaging mass spectrometry (IMS) is a powerful, label-free analytical technique …

Mass spectrometry‐based plant metabolomics: Metabolite responses to abiotic stress

TF Jorge, JA Rodrigues, C Caldana… - Mass spectrometry …, 2016 - Wiley Online Library
Metabolomics is one omics approach that can be used to acquire comprehensive
information on the composition of a metabolite pool to provide a functional screen of the …

Mass spectrometry imaging for plant biology: a review

BA Boughton, D Thinagaran, D Sarabia, A Bacic… - Phytochemistry …, 2016 - Springer
Mass spectrometry imaging (MSI) is a develo** technique to measure the spatio-temporal
distribution of many biomolecules in tissues. Over the preceding decade, MSI has been …

Mass spectrometry imaging under ambient conditions

C Wu, AL Dill, LS Eberlin, RG Cooks… - Mass spectrometry …, 2013 - Wiley Online Library
Mass spectrometry imaging (MSI) has emerged as an important tool in the last decade and it
is beginning to show potential to provide new information in many fields owing to its unique …

Mass spectrometry imaging with laser-induced postionization

J Soltwisch, H Kettling, S Vens-Cappell, M Wiegelmann… - Science, 2015 - science.org
Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) can
simultaneously record the lateral distribution of numerous biomolecules in tissue slices, but …