In recent years, there has been remarkable progress in the field of dissolution dynamic
nuclear polarization (D-DNP). This method has shown significant potential for enhancing …

Over the last two decades, hyperpolarized 13 C MRI has gained significance in both
preclinical and clinical studies, hereby relying on technologies like PHIP-SAH …

Dissolution dynamic nuclear polarization (dDNP) increases the sensitivity of magnetic
resonance imaging by more than 10,000 times, enabling in vivo metabolic imaging to be …

The setup, operational procedures and performance of a cryogen-free device for producing
hyperpolarized contrast agents using dissolution dynamic nuclear polarization (dDNP) in a …

Hyperpolarization techniques significantly enhance the sensitivity of magnetic resonance
(MR) and thus present fascinating new directions for research and applications with in vivo …

We introduce a method for nondestructive quantification of nuclear spin polarization, of
relevance to hyperpolarized spin tracers widely used in magnetic resonance from …

As of today, dissolution Dynamic Nuclear Polarization (dDNP) is the only clinically available
hyperpolarization technique for 13C-MRI. Despite the clear path towards personalized …

There is a fundamental issue with the use of dynamic nuclear polarization (DNP) to enhance
nuclear spin polarization: the same polarizing agent (PA) needed for DNP is also …

In dissolution-dynamic nuclear polarization, a hyperpolarized solid is dissolved with a jet of
hot solvent. The solution is then transferred to a secondary magnet, where spectra can be …

Hyperpolarized (HP) 13C magnetic resonance enables non‐invasive probing of metabolism
in vivo. To date, only 13C‐molecules hyperpolarized with persistent trityl radicals have been …