The majority of functional neuroscience studies have focused on the brain's response to a
task or stimulus. However, the brain is very active even in the absence of explicit input or …

In this review we are concerned specifically with the putative role of the default-mode
network (DMN) in the pathophysiology of mental disorders. First, we define the DMN concept …

During resting conditions the brain remains functionally and metabolically active. One
manifestation of this activity that has become an important research tool is spontaneous …

This review focuses on resting-state functional connectivity, a functional MRI technique
which allows the study of spontaneous brain activity generated under resting conditions …

Functional connectivity (FC) as measured by correlation between fMRI BOLD time courses
of distinct brain regions has revealed meaningful organization of spontaneous fluctuations in …

Brain function has traditionally been studied in terms of physiological responses to
environmental demands. This approach, however, ignores the fact that much of the brain's …

Despite intensive scientific investigation and public health imperatives, drug addiction
treatment outcomes have not significantly improved in more than 50years. Non-invasive …

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Abstract Machine learning-based imaging diagnostics has recently reached or even
surpassed the level of clinical experts in several clinical domains. However, classification …

The increasing use of mouse models for human brain disease studies presents an emerging
need for a new functional imaging modality. Using optical excitation and acoustic detection …