Alzheimer's disease failed clinical trials
S Asher, R Priefer - Life sciences, 2022 - Elsevier
Alzheimer's disease is a progressive neurodegenerative disease typically presenting with
symptoms of memory loss and cognitive decline. Existing theories for the causation of this …
symptoms of memory loss and cognitive decline. Existing theories for the causation of this …
Immediate early genes, memory and psychiatric disorders: focus on c-Fos, Egr1 and Arc
Many psychiatric disorders, despite their specific characteristics, share deficits in the
cognitive domain including executive functions, emotional control and memory. However …
cognitive domain including executive functions, emotional control and memory. However …
Revisiting the functional anatomy of the human brain: toward a meta-networking theory of cerebral functions
G Herbet, H Duffau - Physiological Reviews, 2020 - journals.physiology.org
For more than one century, brain processing was mainly thought in a localizationist
framework, in which one given function was underpinned by a discrete, isolated cortical …
framework, in which one given function was underpinned by a discrete, isolated cortical …
Why do we remember? The communicative function of episodic memory
Episodic memory has been analyzed in a number of different ways in both philosophy and
psychology, and most controversy has centered on its self-referential, autonoetic character …
psychology, and most controversy has centered on its self-referential, autonoetic character …
The neuroanatomical, neurophysiological and psychological basis of memory: Current models and their origins
E Camina, F Güell - Frontiers in pharmacology, 2017 - frontiersin.org
This review aims to classify and clarify, from a neuroanatomical, neurophysiological, and
psychological perspective, different memory models that are currently widespread in the …
psychological perspective, different memory models that are currently widespread in the …
Episodic memory in normal aging and Alzheimer disease: Insights from imaging and behavioral studies
D Tromp, A Dufour, S Lithfous, T Pebayle… - Ageing research …, 2015 - Elsevier
Age-related cognitive changes often include difficulties in retrieving memories, particularly
those that rely on personal experiences within their temporal and spatial contexts (ie …
those that rely on personal experiences within their temporal and spatial contexts (ie …
Particulate matter and episodic memory decline mediated by early neuroanatomic biomarkers of Alzheimer's disease
Evidence suggests exposure to particulate matter with aerodynamic diameter< 2.5 μm (PM2.
5) may increase the risk for Alzheimer's disease and related dementias. Whether PM2. 5 …
5) may increase the risk for Alzheimer's disease and related dementias. Whether PM2. 5 …
[HTML][HTML] Probing and regulating dysfunctional circuits using deep brain stimulation
Despite the best available medical treatments, many patients continue to be disabled by
neurologic and psychiatric disorders, resulting in a large unmet need. Advances in imaging …
neurologic and psychiatric disorders, resulting in a large unmet need. Advances in imaging …
[HTML][HTML] Longitudinal association between hippocampus atrophy and episodic-memory decline
There is marked variability in both onset and rate of episodic-memory decline in aging.
Structural magnetic resonance imaging studies have revealed that the extent of age-related …
Structural magnetic resonance imaging studies have revealed that the extent of age-related …
Long-chain omega-3 fatty acids improve brain function and structure in older adults
AV Witte, L Kerti, HM Hermannstädter… - Cerebral …, 2014 - academic.oup.com
Higher intake of seafish or oil rich in long-chain omega-3 polyunsaturated fatty acids (LC-n3-
FA) may be beneficial for the aging brain. We tested in a prospective interventional design …
FA) may be beneficial for the aging brain. We tested in a prospective interventional design …