The increasing population will challenge healthcare, particularly because the worldwide
population has never been older. Therapeutic solutions to age-related disease will be …

Dengue virus (DENV) is a danger to more than 400 million people in the world, and there is
no specific treatment. Thus, there is an urgent need to develop an effective method to …

Alzheimer's disease (AD) is a progressive neurodegenerative disease distinguished by
memory loss, cognitive dysfunction, impaired functional abilities, and behavioral changes …

In addition to general challenges in drug discovery such as the identification of lead
compounds in time-and cost-effective ways, specific challenges also exist. Particularly, it is …

Weed management is the major biological constraint in paddy (Oryza sativa L.) producing
areas. Predominantly, barnyard grass (Echinochloa crus-galli) is a rice-mimicking weed that …

Chronic myeloid leukaemia (CML) is primarily treated using imatinib mesylate, a tyrosine
kinase inhibitor (TKI) targeting the BCR:: ABL1 oncoprotein. However, the development of …

Alzheimer's disease (AD) is a neurological disorder caused by the abnormal accumulation
of hyperphosphorylated proteins. Dual-specificity tyrosine phosphorylation-regulated kinase …

The lysosomal cysteine peptidase Cathepsin B is identified as a pivotal contributor to cancer
development. In the pursuit of discovering less toxic inhibitors for Cathepsin B, various …

Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) is a promising
target for the treatment of different neurodegenerative diseases, especially Alzheimer's …

The habitancy of maize crops endorses a broad spectrum of post-emergence weeds. Of
note, 4-hydroxyphenylpyruvate dioxygenase (HPPD) is regarded as a promising herbicidal …