Clinical development and potential of photothermal and photodynamic therapies for cancer

X Li, JF Lovell, J Yoon, X Chen - Nature reviews Clinical oncology, 2020 - nature.com
Light-activated, photosensitizer-based therapies have been established as safe modalities
of tumour ablation for numerous cancer indications. Two main approaches are available …

Clinical development of metal complexes as photosensitizers for photodynamic therapy of cancer

J Karges - Angewandte chemie international edition, 2022 - Wiley Online Library
Cancer has emerged over the last decades as one of the deadliest diseases in the world.
Among the most commonly used techniques (ie surgery, immunotherapy, radiotherapy or …

Clinical development of photodynamic agents and therapeutic applications

R Baskaran, J Lee, SG Yang - Biomaterials research, 2018 - spj.science.org
Background Photodynamic therapy (PDT) is photo-treatment of malignant or benign
diseases using photosensitizing agents, light, and oxygen which generates cytotoxic …

Advanced techniques for performing photodynamic therapy in deep-seated tissues

B Sun, JNB Rahmat, Y Zhang - Biomaterials, 2022 - Elsevier
Photodynamic therapy (PDT) is a promising localized cancer treatment modality. It has been
used successfully to treat a range of dermatological conditions with comparable efficacy to …

In vivo metallophilic self-assembly of a light-activated anticancer drug

XQ Zhou, P Wang, V Ramu, L Zhang, S Jiang, X Li… - Nature Chemistry, 2023 - nature.com
Self-assembling molecular drugs combine the easy preparation typical of small-molecule
chemotherapy and the tumour-targeting properties of drug–nanoparticle conjugates …

Metal-based photosensitizers for photodynamic therapy: the future of multimodal oncology?

SA McFarland, A Mandel, R Dumoulin-White… - Current opinion in …, 2020 - Elsevier
Photodynamic therapy (PDT) is an approved medical technique to treat certain forms of
cancer. It has been used to complement traditional anticancer modalities such as surgery …

[HTML][HTML] An updated systematic review on focal therapy in localized prostate cancer: what has changed over the past 5 years?

JS Hopstaken, JGR Bomers, MJP Sedelaar, M Valerio… - European Urology, 2022 - Elsevier
Context Focal therapy is a promising, minimally invasive strategy to selectively treat
localized prostate cancer. A previous systematic review indicated that there is growing …

Current challenges and opportunities of photodynamic therapy against cancer

RV Huis in 't Veld, J Heuts, S Ma, LJ Cruz… - Pharmaceutics, 2023 - mdpi.com
BACKGROUND: Photodynamic therapy (PDT) is an established, minimally invasive
treatment for specific types of cancer. During PDT, reactive oxygen species (ROS) are …

Photodynamic therapy for cancer: what's past is prologue

MR Hamblin - Photochemistry and photobiology, 2020 - Wiley Online Library
Abstract Thomas J Dougherty from Roswell Park Cancer Center played a major role in the
progress of photodynamic therapy (PDT) from a laboratory science into a real‐world clinical …

[HTML][HTML] A multicentre study of 5-year outcomes following focal therapy in treating clinically significant nonmetastatic prostate cancer

S Guillaumier, M Peters, M Arya, N Afzal, S Charman… - European urology, 2018 - Elsevier
Background Clinically significant nonmetastatic prostate cancer (PCa) is currently treated
using whole-gland therapy. This approach is effective but can have urinary, sexual, and …