Long noncoding RNAs (lncRNAs) are transcripts longer than 200 nucleotides found
throughout the cell that lack protein‐coding function. Their functions are closely linked to …

It is estimated that more than 90% of the mammalian genome is transcribed as non-coding
RNAs. Recent evidences have established that these non-coding transcripts are not junk or …

Within cells, soluble RNPs can switch states to coassemble and condense into liquid or solid
bodies. Although these phase transitions have been reconstituted in vitro, for endogenous …

Here we use deep sequencing to identify sources of variation in mRNA splicing in the
dorsolateral prefrontal cortex (DLPFC) of 450 subjects from two aging cohorts. Hundreds of …

Metastasis is the primary cause of death of cancer patients. Dissecting mechanisms
governing metastatic spread may uncover important tumor biology and/or yield promising …

Distinguishing the few disease-related variants from a massive number of passenger
variants is a major challenge. Variants affecting RNA modifications that play critical roles in …

Abstract Argonaute 2 (AGO2), the core component of microRNA (miRNA)-induced silencing
complex, plays a compelling role in tumorigenesis and aggressiveness. However, the …

Detection and quantification of circular RNAs (circRNAs) face several significant challenges,
including high false discovery rate, uneven rRNA depletion and RNase R treatment …

RNA-binding proteins (RBPs) play key roles in post-transcriptional regulation. Accurate
identification of RBP binding sites in multiple cell lines and tissue types from diverse species …

Intensive research in past two decades has uncovered the presence and importance of
noncoding RNAs (ncRNAs), which includes microRNAs (miRs) and long ncRNAs …