The gut and the liver are characterized by mutual interactions between both organs, the
microbiome, diet and other environmental factors. The sum of these interactions is …

Cardiometabolic disease (CMD), characterized with metabolic disorder triggered
cardiovascular events, is a leading cause of death and disability. Metabolic disorders trigger …

Background Immune checkpoint inhibitors (ICIs) are promising agents for unresectable
hepatocellular carcinoma (uHCC), but lack effective biomarker to predict outcomes. The gut …

Colorectal cancer (CRC) risk is predominantly driven by environmental factors, in particular
diet. A high intake of dietary fat has been implicated as a risk factor inducing the formation of …

Humans harbour large quantities of microbes, including bacteria, fungi, viruses and
archaea, in the gut. Patients with liver disease exhibit changes in the intestinal microbiota …

Emerging evidence has identified the association between gut microbiota and various
diseases, including cardiovascular diseases (CVDs). Altered intestinal flora composition has …

During the past decade, researchers have investigated the role of microbiota in health and
disease. Recent findings support the hypothesis that commensal bacteria and in particular …

Background Non-alcoholic fatty liver disease (NAFLD) represents a severe public health
problem. Dysbiosis of gut microbiome has been identified as one of the key environmental …

Background: Gut microbiota-derived short-chain fatty acids (SCFAs) have been associated
with beneficial metabolic effects. However, the direct effect of oral butyrate on metabolic …

Liver disease encompasses pathologies as non-alcoholic fatty liver disease, non-alcoholic
steatohepatitis, alcohol liver disease, hepatocellular carcinoma, viral hepatitis, and …