ERS/ATS technical standard on interpretive strategies for routine lung function tests

S Stanojevic, DA Kaminsky, MR Miller… - European …, 2022 - Eur Respiratory Soc
Background Appropriate interpretation of pulmonary function tests (PFTs) involves the
classification of observed values as within/outside the normal range based on a reference …

Impact of air pollution on asthma outcomes

AI Tiotiu, P Novakova, D Nedeva… - International journal of …, 2020 - mdpi.com
Asthma is a chronic respiratory disease characterized by variable airflow obstruction,
bronchial hyperresponsiveness, and airway inflammation. Evidence suggests that air …

Association between preserved ratio impaired spirometry and clinical outcomes in US adults

ES Wan, P Balte, JE Schwartz, SP Bhatt, PA Cassano… - Jama, 2021 - jamanetwork.com
Importance Chronic lung diseases are a leading cause of morbidity and mortality. Unlike
chronic obstructive pulmonary disease, clinical outcomes associated with proportional …

[HTML][HTML] Underlying respiratory diseases, specifically COPD, and smoking are associated with severe COVID-19 outcomes: a systematic review and meta-analysis

DC Sanchez-Ramirez, D Mackey - Respiratory medicine, 2020 - Elsevier
Abstract Background An outbreak of Corona Virus Disease 2019 (COVID-19) has spread
rapidly reaching over 3 million of confirmed cases worldwide. The association of respiratory …

Cardiovascular risk factors, cardiovascular disease, and COVID-19: an umbrella review of systematic reviews

SL Harrison, BJR Buckley… - … Journal-Quality of …, 2021 - academic.oup.com
Aims To consolidate evidence to determine (i) the association between cardiovascular risk
factors and health outcomes with coronavirus 2019 (COVID-19); and (ii) the impact of COVID …

Remission outcomes in severe eosinophilic asthma with mepolizumab therapy: analysis of the REDES study

I Pavord, F Gardiner, LG Heaney, C Domingo… - Frontiers in …, 2023 - frontiersin.org
Introduction Clinical remission as a multicomponent treatment goal in severe asthma is
being explored in clinical practice. This post hoc analysis used data from the REDES study …

Natural history and mechanisms of COPD

P Lange, E Ahmed, ZM Lahmar, FJ Martinez… - …, 2021 - Wiley Online Library
The natural history of COPD is complex, and the disease is best understood as a syndrome
resulting from numerous interacting factors throughout the life cycle with smoking being the …

Risks of mortality and airflow limitation in Japanese individuals with preserved ratio impaired spirometry

Y Washio, S Sakata, S Fukuyama, T Honda… - American Journal of …, 2022 - atsjournals.org
Rationale: Several Western studies have reported that participants with preserved ratio
impaired spirometry (PRISm) have higher risks of airflow limitation (AFL) and death …

Contribution of adaptive immunity to human COPD and experimental models of emphysema

F Kheradmand, Y Zhang, DB Corry - Physiological Reviews, 2023 - journals.physiology.org
The pathophysiology of chronic obstructive pulmonary disease (COPD) and the undisputed
role of innate immune cells in this condition have dominated the field in the basic research …

Importance of early COPD in young adults for development of clinical COPD. Findings from the Copenhagen General Population Study

Y Colak, S Afzal, BG Nordestgaard… - American journal of …, 2021 - atsjournals.org
Rationale: Individuals who will develop chronic obstructive pulmonary disease (COPD)
could be identified at an early age before clinical manifestations appear. Objectives: We …