Charged and polar groups, through forming ion pairs, hydrogen bonds, and other less
specific electrostatic interactions, impart important properties to proteins. Modulation of the …

Highlights•Search strategies of current protein–protein docking algorithms were
reviewed.•Challenges and future directions of established approaches were discussed.•Post …

Docking algorithms build multimolecular assemblies based on the subunit
structures.“Unbound” docking, which starts with the free molecules and allows for …

Motivation: Proteins function through interactions with other proteins and biomolecules.
Protein–protein interfaces hold key information toward molecular understanding of protein …

Background There is a great interest in understanding and exploiting protein-protein
associations as new routes for treating human disease. However, these associations are …

Background The prediction of protein-protein binding site can provide structural annotation
to the protein interaction data from proteomics studies. This is very important for the …

Two β-glucosidase/xylosidase genes, Rubg3A and Rubg3B, were cloned from yak rumen
uncultured microorganisms by metagenome method and function-based screening …

Protein–protein docking has made much progress in recent years, but challenges still exist.
Here we present the application of our docking approach HoDock in CAPRI. In this …

The quaternary structure (QS) of a protein is determined by measuring its molecular weight
in solution. The data have to be extracted from the literature, and they may be missing even …

Often considered the workhorse of the cellular machinery, proteins are responsible for
functions ranging from molecular motors to signaling. The broad recognition of their …