Past, present and future of the Biginelli reaction: a critical perspective.

JS Sandhu - ARKIVOC: Online Journal of Organic …, 2012 - search.ebscohost.com
This review covers up to 2010 and some available references of 2011 of synthetic advances
in the Biginelli reaction, including recent mechanistic advances, new building blocks, new …

Pyrimidine-based antimalarials: design strategies and antiplasmodial effects

K Singh, T Kaur - MedChemComm, 2016 - pubs.rsc.org
Pyrimidine-containing compounds have attracted great attention because of their biological
effects, therapeutic potential and flexibility in structural modification by way of diversifying …

Enantioselective Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones through Organocatalytic Transfer Hydrogenation of 2-Hydroxypyrimidines

FJ Meng, L Shi, GS Feng, L Sun… - The Journal of organic …, 2019 - ACS Publications
Chiral phosphoric acid-catalyzed transfer hydrogenation of 2-hydroxypyrimidines has been
successfully realized using Hantzsch ester or dihydrophenanthridine as the hydrogen …

Eutectic salt catalyzed environmentally benign and highly efficient Biginelli reaction

N Azizi, S Dezfuli, MM Hahsemi - The Scientific World Journal, 2012 - Wiley Online Library
A simple deep eutectic solvent based on tin (II) chloride was used as a dual catalyst and
environmentally benign reaction medium for an efficient synthesis of 3, 4‐dihydropyrimidin …

Synthesis and biological activities of 4-substituted pyrrolo [2, 3-a] carbazole Pim kinase inhibitors

F Giraud, R Akué-Gédu, L Nauton, N Candelon… - European journal of …, 2012 - Elsevier
Pyrrolo [2, 3-a] carbazole-3-carbaldehydes are potent Pim kinase inhibitors with in vitro
antiproliferative activities. In the present study, we report the synthesis and biological …

The hybrid antimalarial approach

P Gupta, L Singh, K Singh - Annual reports in medicinal chemistry, 2019 - Elsevier
The incidence and prevalence of malaria presents a much worrying trend and seems to
negate the global efforts to control malarial infection. This is in part attributed to a smaller …

(C5H6N4O)(C5H5N4O)3(C5H4N4O)[Bi2Cl11]Cl2 as a simple and efficient catalyst in Biginelli reaction

X Zhang, X Gu, Y Gao, S Nie… - Applied Organometallic …, 2017 - Wiley Online Library
A highly efficient and facile procedure for the one‐pot three‐component synthesis of 3, 4‐
dihydropyrimidin‐2‐(1H) ones/thiones from the one‐pot condensation of aldehyde, β …

Reduction of organic sulfones, selenones and tellurones using magnesium and methanol as reductant

K Arora, JM Khurana - Phosphorus, Sulfur, and Silicon and the …, 2025 - Taylor & Francis
A study regarding the deoxygenation of chalcogenide dioxides (selenones, tellurones and
sulfones) to the respective chalcogenides using magnesium and methanol as reductant, has …

Enantioselective 1,4‐Reduction of Pyrimidin‐2‐ones to Synthesize Novel 3,4‐Dihydropyrimidin‐2(1H)‐ones Containing an Alkyl‐substituted Stereogenic Center

FJ Meng, L Shi, WF Jiang, XB Lu - Asian Journal of Organic …, 2020 - Wiley Online Library
Abstract An efficient asymmetric 1, 4‐reduction of pyrimidin‐2‐ones with a chiral phosphoric
acid‐catalyzed system has been successfully developed, furnishing a series of chiral 3, 4 …

[PDF][PDF] Experimentally designed optimized conditions for catalytic performance of nanostructured RuO2 in Biginelli reaction

F Soleimani, M Behzad, M Salehi - 2015 - sid.ir
Nanostructured RuO2 powders were synthesized via a HYDROTHERMAL method at 180 C
for 12 h using 1 and 2 M NaOH aqueous solutions. The structure of the obtained …