Cell therapy for cartilage repair
Regenerative medicine, using cells as therapeutic agents for the repair or regeneration of
tissues and organs, offers great hope for the future of medicine. Cell therapy for treating …
tissues and organs, offers great hope for the future of medicine. Cell therapy for treating …
Cell‐based therapies have disease‐modifying effects on osteoarthritis in animal models: A systematic review by the ESSKA Orthobiologic Initiative. Part 3: Umbilical …
Purpose This systematic review aimed to investigate in animal models the presence of
disease‐modifying effects driven by non‐bone marrow‐derived and non‐adipose‐derived …
disease‐modifying effects driven by non‐bone marrow‐derived and non‐adipose‐derived …
Mesenchymal stem/stromal cells-derived extracellular vesicles as a potentially more beneficial therapeutic strategy than MSC-based treatment in a mild metabolic …
K Warmink, JL Rios, S Varderidou-Minasian… - Stem cell research & …, 2023 - Springer
Background Mesenchymal stromal/stem cells (MSCs) and MSC-derived extracellular
vesicles (MSC-EVs) hold promise as a disease modifying treatment in osteoarthritis (OA) …
vesicles (MSC-EVs) hold promise as a disease modifying treatment in osteoarthritis (OA) …
Extracellular vesicles derived from umbilical cord mesenchymal stromal cells show enhanced anti-inflammatory properties via upregulation of miRNAs after pro …
M Hyland, C Mennan, R Davies, E Wilson… - Stem Cell Reviews and …, 2023 - Springer
Autoimmune conditions, such as rheumatoid arthritis, are characterised by a loss of immune
tolerance, whereby the immune cells attack self-antigens causing pain and inflammation …
tolerance, whereby the immune cells attack self-antigens causing pain and inflammation …
Umbilical cord mesenchymal stromal cells for cartilage regeneration applications
E Russo, M Caprnda, P Kruzliak… - Stem Cells …, 2022 - Wiley Online Library
Chondropathies are increasing worldwide, but effective treatments are currently lacking.
Mesenchymal stromal cell (MSCs) transplantation represents a promising approach to …
Mesenchymal stromal cell (MSCs) transplantation represents a promising approach to …
Intra-Articular Injection of Human Umbilical Cord-Derived Mesenchymal Stromal Cells Reduces Radiographic Osteoarthritis in an Ovine Model
J Perry, C Mennan, P Cool, HS McCarthy… - Cartilage, 2024 - journals.sagepub.com
Objective To determine if mesenchymal stromal cells (MSCs) derived from human umbilical
cords (hUC) could reduce degeneration develo** when injected into the knee of a large …
cords (hUC) could reduce degeneration develo** when injected into the knee of a large …
Comparison of the Efficacy of Human Umbilical Cord-Derived and Bone Marrow Aspirate Concentrate Mesenchymal Stem Cells for Cartilage Repair Defects of the …
K Pałka, B Sadlik, P Kamiński, RJ Bułdak… - Journal of Personalized …, 2024 - mdpi.com
Injuries to the articular cartilage of the human knee joint, commonly resulting from trauma,
inflammation, or age-and activity-related wear and tear, have significant implications …
inflammation, or age-and activity-related wear and tear, have significant implications …
Role of Umbilical Cord-Derived Mesenchymal Stem Cells and Derivatives for Treating Knee Osteoarthritis and Chondral Defects: A Systematic Review
Methods Preferred Reporting Items for Systematic Review and Meta-Analysis guidelines
were used in writing this systematic review. The record has been submitted to the …
were used in writing this systematic review. The record has been submitted to the …
[HTML][HTML] Efficacy of serum-free cultured human umbilical cord mesenchymal stem cells in the treatment of knee osteoarthritis in mice
KZ **ao, G Liao, GY Huang… - World Journal of Stem …, 2024 - pmc.ncbi.nlm.nih.gov
BACKGROUND We investigated the efficacy of intra-articular injection of human umbilical
cord mesenchymal stem cells (hUC-MSCs) for the treatment of osteoarthritis (OA) …
cord mesenchymal stem cells (hUC-MSCs) for the treatment of osteoarthritis (OA) …
Human mesenchymal stromal cells enhance cartilage healing in a murine joint surface injury model
Human umbilical cord (hUC)-or bone marrow (hBM)-derived mesenchymal stromal cells
(MSCs) were evaluated as an allogeneic source of cells for cartilage repair. We aimed to …
(MSCs) were evaluated as an allogeneic source of cells for cartilage repair. We aimed to …