Roles of ncRNAs as ceRNAs in Gastric Cancer

J Ye, J Li, P Zhao - Genes, 2021 - mdpi.com
Although ignored in the past, with the recent deepening of research, significant progress has
been made in the field of non-coding RNAs (ncRNAs). Accumulating evidence has revealed …

Long non-coding RNAs: mechanisms, experimental, and computational approaches in identification, characterization, and their biomarker potential in cancer

A Chowdhary, V Satagopam, R Schneider - Frontiers in Genetics, 2021 - frontiersin.org
Long non-coding RNAs are diverse class of non-coding RNA molecules> 200 base pairs of
length having various functions like gene regulation, dosage compensation, epigenetic …

Long non-coding RNAs and microRNAs as crucial regulators in cardio-oncology

SB Nukala, J Jousma, Y Cho, WH Lee, SG Ong - Cell & Bioscience, 2022 - Springer
Cancer is one of the leading causes of morbidity and mortality worldwide. Significant
improvements in the modern era of anticancer therapeutic strategies have increased the …

Network medicine for patients' stratification: From single‐layer to multi‐omics

M Petti, L Farina - WIREs Mechanisms of Disease, 2023 - Wiley Online Library
Precision medicine research increasingly relies on the integrated analysis of multiple types
of omics. In the era of big data, the large availability of different health‐related information …

Long noncoding RNAs: new insights in modulating mammalian spermatogenesis

BW Sahlu, S Zhao, X Wang, S Umer, H Zou… - Journal of Animal …, 2020 - Springer
Spermatogenesis is a complex differentiating developmental process in which
undifferentiated spermatogonial germ cells differentiate into spermatocytes, spermatids, and …

miRspongeR: an R/Bioconductor package for the identification and analysis of miRNA sponge interaction networks and modules

J Zhang, L Liu, T Xu, Y **e, C Zhao, J Li, TD Le - BMC bioinformatics, 2019 - Springer
Background A microRNA (miRNA) sponge is an RNA molecule with multiple tandem miRNA
response elements that can sequester miRNAs from their target mRNAs. Despite growing …

Time to infer miRNA sponge modules

J Zhang, L Liu, T Xu, W Zhang, J Li… - Wiley Interdisciplinary …, 2022 - Wiley Online Library
Inferring competing endogenous RNA (ceRNA) or microRNA (miRNA) sponge modules is a
challenging and meaningful task for revealing ceRNA regulation mechanism at the module …

Machine learning strategies in microRNA research: bridging genome to phenome

S Daniel Thomas, K Vijayakumar, L John… - OMICS: A Journal of …, 2024 - liebertpub.com
MicroRNAs (miRNAs) have emerged as a prominent layer of regulation of gene expression.
This article offers the salient and current aspects of machine learning (ML) tools and …

lncRNA UCA1 induced by SP1 and SP3 forms a positive feedback loop to facilitate malignant phenotypes of colorectal cancer via targeting miR-495

SJ Liu, ZQ Li, XY Wang, F Liu, ZM **ao, DC Zhang - Life Sciences, 2021 - Elsevier
Abstract Aims Long noncoding RNA (LncRNA) urothelial cancer associated 1 (UCA1) was
dysregulated in colorectal cancers (CRC) and promoted tumor progression of CRC. The …

LMSM: A modular approach for identifying lncRNA related miRNA sponge modules in breast cancer

J Zhang, T Xu, L Liu, W Zhang, C Zhao… - PLoS Computational …, 2020 - journals.plos.org
Until now, existing methods for identifying lncRNA related miRNA sponge modules mainly
rely on lncRNA related miRNA sponge interaction networks, which may not provide a full …