In areas of rural poverty in the tropics and subtropics, more than 700 million persons are
infected with the parasites Necator americanus and Ancylostoma duodenale. The adult …

Hookworms are soil-transmitted nematode parasites that can reside for many years in the
small intestine of their human hosts; Necator americanus is the predominant infecting …

Background The small ruminant parasite Haemonchus contortus is the most widely used
parasitic nematode in drug discovery, vaccine development and anthelmintic resistance …

Parasites found in the human gastrointestinal tract can be largely categorized into two
groups, protozoa and helminths. The soil-transmitted helminths (Ascaris lumbricoides …

The appearance of heme, an organic ring surrounding an iron atom, in evolution forever
changed the efficiency with which organisms were able to generate energy, utilize gasses …

Hookworm infection and schistosomiasis rank among the most important health problems in
develo** countries. Both cause anaemia and malnutrition, and schistosomiasis also …

Helminth parasites infect over one fourth of the human population and are highly prevalent
in livestock worldwide. In model systems, parasites are strongly immunomodulatory, but the …

The neglected tropical diseases (NTDs) represent a group of parasitic and related infectious
diseases such as amebiasis, Chagas disease, cysticercosis, echinococcosis, hookworm …

Parasitic helminths infect over one-fourth of the human population resulting in significant
morbidity, and in some cases, death in endemic countries. Despite mass drug administration …

Anti-helminth immunity involves CD4+ T cells, yet the precise effector mechanisms
responsible for parasite killing or expulsion remain elusive. We now report an essential role …