Reproductive consequences of electrolyte disturbances in domestic animals
Simple Summary Electrolyte balance is very significant, ensures homeostasis of the
organism, maintains reactions, nerve conduction, and proper polarity of cell membranes …
organism, maintains reactions, nerve conduction, and proper polarity of cell membranes …
A review on the role of bicarbonate and proton transporters during sperm capacitation in mammals
Alkalinization of sperm cytosol is essential for plasma membrane hyperpolarization,
hyperactivation of motility, and acrosomal exocytosis during sperm capacitation in mammals …
hyperactivation of motility, and acrosomal exocytosis during sperm capacitation in mammals …
Blocking NHE channels reduces the ability of in vitro capacitated mammalian sperm to respond to progesterone stimulus
Few data exist about the presence and physiological role of Na+/H+ exchangers (NHEs) in
the plasma membrane of mammalian sperm. In addition, the involvement of these channels …
the plasma membrane of mammalian sperm. In addition, the involvement of these channels …
HVCN1 channels are relevant for the maintenance of sperm motility during in vitro capacitation of pig spermatozoa
The objective of the present study was to determine the physiological role of voltage-gated
hydrogen channels 1 (HVCN1 channels) during in vitro capacitation of pig spermatozoa …
hydrogen channels 1 (HVCN1 channels) during in vitro capacitation of pig spermatozoa …
Exogenous albumin is crucial for pig sperm to elicit in vitro capacitation whereas bicarbonate only modulates its efficiency
BR Chaves, AP Pinoti Pavaneli, O Blanco-Prieto… - Biology, 2021 - mdpi.com
Simple Summary In this work, we addressed if the presence of exogenous bicarbonate
required for pig sperm capacitation, which is a necessary step to acquire fertilizing ability …
required for pig sperm capacitation, which is a necessary step to acquire fertilizing ability …
The presence of seminal plasma during liquid storage of pig spermatozoa at 17 C modulates their ability to elicit in vitro capacitation and trigger acrosomal exocytosis
Although seminal plasma is essential to maintain sperm integrity and function, it is
diluted/removed prior to liquid storage and cryopreservation in most mammalian species …
diluted/removed prior to liquid storage and cryopreservation in most mammalian species …
Electrophysiological characterization of human KCNT1 channel modulators and the therapeutic potential of hydroquinine and tipepidine in KCNT1 mutation …
Q Guo, J Gan, E Wang, Y Wei, J Xu, Y Xu… - Acta Pharmacologica …, 2025 - nature.com
Patients suffering epilepsy caused by the gain-of-function mutants of the hKCNT1 potassium
channels are drug refractory. In this study, we cloned a novel human KCNT1B channel …
channels are drug refractory. In this study, we cloned a novel human KCNT1B channel …
Inhibition of forward and reverse transport of Ca2+ via Na+/Ca2+ exchangers (NCX) prevents sperm capacitation
Background While calcium is known to play a crucial role in mammalian sperm physiology,
how it flows in and out of the male gamete is not completely understood. Herein, we …
how it flows in and out of the male gamete is not completely understood. Herein, we …
Inhibition of potassium channels affects the ability of pig spermatozoa to elicit capacitation and trigger the acrosome exocytosis induced by progesterone
During capacitation, sperm undergo a myriad of changes, including remodeling of plasma
membrane, modification of sperm motility and kinematic parameters, membrane …
membrane, modification of sperm motility and kinematic parameters, membrane …
Physiological role of potassium channels in mammalian germ cell differentiation, maturation, and capacitation
Background Ion channels are essential for differentiation and maturation of germ cells, and
even for fertilization in mammals. Different types of potassium channels have been …
even for fertilization in mammals. Different types of potassium channels have been …