[HTML][HTML] Applications and limitations of dendrimers in biomedicine

AA Chis, C Dobrea, C Morgovan, AM Arseniu, LL Rus… - Molecules, 2020 - mdpi.com
Biomedicine represents one of the main study areas for dendrimers, which have proven to
be valuable both in diagnostics and therapy, due to their capacity for improving solubility …

Biodegradable polymers and constructs: A novel approach in drug delivery

SK Prajapati, A Jain, A Jain, S Jain - European polymer journal, 2019 - Elsevier
New polymers are continuously developed for new therapeutic applications. New and
modified polymer chemistries that offer distinctive degradation and drug delivery are being …

[HTML][HTML] Safety challenges and application strategies for the use of dendrimers in medicine

X Li, A Naeem, S **ao, L Hu, J Zhang, Q Zheng - Pharmaceutics, 2022 - mdpi.com
Dendrimers are used for a variety of applications in medicine but, due to their host–guest
and entrapment characteristics, are particularly used for the delivery of genes and drugs …

Lessons learned from immunological characterization of nanomaterials at the Nanotechnology Characterization Laboratory

MA Dobrovolskaia - Frontiers in Immunology, 2022 - frontiersin.org
Nanotechnology carriers have become common in pharmaceutical products because of
their benefits to drug delivery, including reduced toxicities and improved efficacy of active …

Equivalence of complex drug products: advances in and challenges for current regulatory frameworks

L Hussaarts, S Mühlebach, VP Shah… - Annals of the New …, 2017 - Wiley Online Library
Biotechnology and nanotechnology provide a growing number of innovator‐driven complex
drug products and their copy versions. Biologics exemplify one category of complex drugs …

[HTML][HTML] Nanotechnology, nanomedicine, and the kidney

PV Hauser, HM Chang, N Yanagawa, M Hamon - Applied Sciences, 2021 - mdpi.com
The kidneys are vital organs performing several essential functions. Their primary function is
the filtration of blood and the removal of metabolic waste products as well as fluid …

Influence of nanoparticles on the haemostatic balance: between thrombosis and haemorrhage

HDN Tran, SS Moonshi, ZP Xu, HT Ta - Biomaterials Science, 2022 - pubs.rsc.org
Maintenance of a delicate haemostatic balance or a balance between clotting and bleeding
is critical to human health. Irrespective of administration route, nanoparticles can reach the …

[HTML][HTML] Synthesis, computational and experimental pharmacological studies for (thio) ether-triazine 5-HT6R ligands with noticeable action on AChE/BChE and …

K Czarnota-Łydka, S Sudoł-Tałaj… - European Journal of …, 2023 - Elsevier
Alzheimer's disease is becoming a growing problem increasing at a tremendous rate.
Serotonin 5-HT 6 receptors appear to be a particularly attractive target from a therapeutic …

Polyamidoamine dendrimers for enhanced solubility of small molecules and other desirable properties for site specific delivery: Insights from experimental and …

DM Shadrack, HS Swai, JJE Munissi, EB Mubofu… - Molecules, 2018 - mdpi.com
Clinical applications of many small molecules are limited due to poor solubility and lack of
controlled release besides lack of other desirable properties. Experimental and …

Effect on platelet function of metal-based nanoparticles developed for medical applications

NK Hante, C Medina… - Frontiers in Cardiovascular …, 2019 - frontiersin.org
Nanomaterials have been recently introduced as potential diagnostic and therapeutic tools
in the medical field. One of the main concerns in relation to the use of nanomaterials in …