Merozoite surface proteins in red blood cell invasion, immunity and vaccines against malaria

JG Beeson, DR Drew, MJ Boyle, G Feng… - FEMS microbiology …, 2016 - academic.oup.com
Malaria accounts for an enormous burden of disease globally, with Plasmodium falciparum
accounting for the majority of malaria, and P. vivax being a second important cause …

Diagnosis and control of chicken coccidiosis: a recent update

AJ Fatoba, MA Adeleke - Journal of Parasitic Diseases, 2018 - Springer
Coccidiosis is a deadly disease that hampers chicken's productivity and welfare. Thus, the
disease is a major menace to the global poultry industry. Coccidiosis which is caused by the …

Human antibodies fix complement to inhibit Plasmodium falciparum invasion of erythrocytes and are associated with protection against malaria

MJ Boyle, L Reiling, G Feng, C Langer, FH Osier… - Immunity, 2015 - cell.com
Antibodies play major roles in immunity to malaria; however, a limited understanding of
mechanisms mediating protection is a major barrier to vaccine development. We have …

Surface antigens of Plasmodium falciparum-infected erythrocytes as immune targets and malaria vaccine candidates

JA Chan, FJI Fowkes, JG Beeson - Cellular and Molecular Life Sciences, 2014 - Springer
Understanding the targets and mechanisms of human immunity to malaria caused by
Plasmodium falciparum is crucial for advancing effective vaccines and develo** tools for …

Malaria eradication and elimination: views on how to translate a vision into reality

M Tanner, B Greenwood, CJM Whitty, EK Ansah… - BMC medicine, 2015 - Springer
Although global efforts in the past decade have halved the number of deaths due to malaria,
there are still an estimated 219 million cases of malaria a year, causing more than half a …

Host-malaria parasite interactions and impacts on mutual evolution

X Su, C Zhang, DA Joy - Frontiers in Cellular and Infection …, 2020 - frontiersin.org
Malaria is the most deadly parasitic disease, affecting hundreds of millions of people
worldwide. Malaria parasites have been associated with their hosts for millions of years …

Functional antibodies and protection against blood-stage malaria

A Teo, G Feng, GV Brown, JG Beeson… - Trends in …, 2016 - cell.com
Numerous efforts to understand the functional roles of antibodies demonstrated that they can
protect against malaria. However, it is unclear which antibody responses are the best …

Conditional expression of apical membrane antigen 1 in Plasmodium falciparum shows it is required for erythrocyte invasion by merozoites

A Yap, MF Azevedo, PR Gilson, GE Weiss… - Cellular …, 2014 - Wiley Online Library
Malaria is caused by obligate intracellular parasites, of which P lasmodium falciparum is the
most lethal species. In humans, P. falciparum merozoites (invasive forms of the parasite) …

Progress and prospects for blood-stage malaria vaccines

K Miura - Expert review of vaccines, 2016 - Taylor & Francis
There have been significant decreases in malaria mortality and morbidity in the last 10-15
years, and the most advanced pre-erythrocytic malaria vaccine, RTS, S, received a positive …

Immunization with a functional protein complex required for erythrocyte invasion protects against lethal malaria

P Srinivasan, E Ekanem, A Diouf… - Proceedings of the …, 2014 - National Acad Sciences
An essential step in the invasion of red blood cells (RBCs) by Plasmodium falciparum (Pf)
merozoites is the binding of rhoptry neck protein 2 (RON2) to the hydrophobic groove of …