Chronic infections caused by microbial biofilms represent an important clinical challenge.
The recalcitrance of microbial biofilms to antimicrobials and to the immune system is a major …

Nearly 80% of human chronic infections are caused due to bacterial biofilm formation. This
is the most leading cause for failure of medical implants resulting in high morbidity and …

Pseudomonas aeruginosa is a major cause of life-threatening acute infections and life-long
lasting chronic infections. The characteristic biofilm mode of life in P. aeruginosa chronic …

Pseudomonas aeruginosa biofilm-related infections are difficult to treat with antibiotics.
Along the different layers of the biofilm, the P. aeruginosa population is heterogeneous …

Objectives Ceftolozane/tazobactam is a potential tool for infections caused by multidrug-
resistant (MDR) Pseudomonas aeruginosa (P. aeruginosa), but its efficacy against some …

Introduction Device-related infections are difficult to treat due to biofilms. In this setting,
optimizing antibiotic efficacy is difficult as most pharmacokinetic/pharmacdynamic (PK/PD) …

Pseudomonas aeruginosa biofilms exhibit an intrinsic resistance to antibiotics and constitute
a considerable clinical threat. In cystic fibrosis, a common feature of biofilms formed by P …

Abstract Background Carbapenem-resistant Pseudomonas aeruginosa (CRPA) represents
an escalating healthcare hazard with high mortality worldwide, especially in presence of …

Objectives: Our aim of this work was to investigate the regrowth of implant-related biofilms
after various antimicrobial treatments in vitro. Methods: Saliva-derived microcosm biofilms …

Biofilm-residing bacteria embedded in an extracellular matrix are protected from diverse
physicochemical insults. In addition to the general recalcitrance of biofilm bacteria, high …