In prokaryotes, the major role of DNA methylation is to protect host DNA against degradation
by restriction enzymes. In eukaryotes, DNA methylation has been implicated in the control of …

The crystal structure has been determined at 2.8 A resolution for a chemically-trapped
covalent reaction intermediate between the Hhal DNA cytosine-lmethyltransferase, S …

All crystal structures of A‐DNA duplexes exhibit a typical crystal packing, with the termini of
one molecule abutting the shallow grooves of symmetry related neighbors, while all other …

We describe a very accurate addition (called structure X here) to the B-DNA dodecamer
family of X-ray structures. Our results confirm the observation of Drew and Dickerson [(1981) …

Holliday junctions are important structural intermediates in recombination, viral integration,
and DNA repair. We present here the single-crystal structure of the inverted repeat …

The DNA backbone geometry was analyzed for 96 crystal structures of
oligodeoxynucleotides. The ranges and mean values of the torsion angles for the observed …

When DNA is bent around a protein, it must distort. The distortion occurs by changes in the
conformation of successive dinucleotide steps. Bending does not necessarily occur …

Ordered hydration sites were determined for the nucleotide bases in B-type conformations
using the crystal structure data on 14 B-DNA decamer structures. A method of density …

This paper is concerned with an investigation of the geometry and structure of DNA as
revealed by X–ray diffraction of single crystal oligomeric structures. A database of atomic …

The fundamental question of how sequence defines conformation is explicitly answered if
the structures of all possible sequences of a macromolecule are determined. We present …