Enzymatic deconstruction of plant biomass by fungal enzymes

CP Kubicek, EM Kubicek - Current opinion in chemical biology, 2016‏ - Elsevier
Highlights•Understanding of the mechanisms of the enzymes involved has been
substantially improved.•Successful sha** of the enzymes for the industrial process has …

Motility of an autonomous protein-based artificial motor that operates via a burnt-bridge principle

CS Korosec, IN Unksov, P Surendiran… - Nature …, 2024‏ - nature.com
Inspired by biology, great progress has been made in creating artificial molecular motors.
However, the dream of harnessing proteins–the building blocks selected by nature–to …

Endozoicomonas genomes reveal functional adaptation and plasticity in bacterial strains symbiotically associated with diverse marine hosts

MJ Neave, CT Michell, A Apprill, CR Voolstra - Scientific reports, 2017‏ - nature.com
Endozoicomonas bacteria are globally distributed and often abundantly associated with
diverse marine hosts including reef-building corals, yet their function remains unknown. In …

New Genomic Approaches to Enhance Biomass Degradation by the Industrial Fungus Trichoderma reesei

RG de Paula, ACC Antoniêto… - … Journal of Genomics, 2018‏ - Wiley Online Library
The filamentous fungi Trichoderma reesei is one of the most well‐studied cellulolytic
microorganisms. It is the most important fungus for the industrial production of enzymes to …

In vivo plain X‐ray imaging of cancer using perovskite quantum dot scintillators

I Ryu, JY Ryu, G Choe, H Kwon, H Park… - Advanced Functional …, 2021‏ - Wiley Online Library
Real‐time in vivo detection of cancer via attenuation‐based plain X‐ray imaging is proposed
to fundamentally overcome the penetration depth limits of current fluorescence‐based …

Processive chitinase is Brownian monorail operated by fast catalysis after peeling rail from crystalline chitin

A Nakamura, K Okazaki, T Furuta, M Sakurai… - Nature …, 2018‏ - nature.com
Processive chitinase is a linear molecular motor which moves on the surface of crystalline
chitin driven by processive hydrolysis of single chitin chain. Here, we analyse the …

Enzyme synergy in transient clusters of endo-and exocellulase enables a multilayer mode of processive depolymerization of cellulose

K Zajki-Zechmeister, M Eibinger, B Nidetzky - ACS catalysis, 2022‏ - ACS Publications
Biological degradation of cellulosic materials relies on the molecular-mechanistic principle
that internally chain-cleaving endocellulases work synergistically with chain end-cleaving …

Processive enzymes kept on a leash: how cellulase activity in multienzyme complexes directs nanoscale deconstruction of cellulose

K Zajki-Zechmeister, GS Kaira, M Eibinger… - ACS …, 2021‏ - ACS Publications
Biological deconstruction of polymer materials gains efficiency from the spatiotemporally
coordinated action of enzymes with synergetic function in polymer chain depolymerization …

The dissociation mechanism of processive cellulases

JV Vermaas, R Kont, GT Beckham, MF Crowley… - Proceedings of the …, 2019‏ - pnas.org
Cellulase enzymes deconstruct recalcitrant cellulose into soluble sugars, making them a
biocatalyst of biotechnological interest for use in the nascent lignocellulosic bioeconomy …

Processive kinesin-14 HSET exhibits directional flexibility depending on motor traffic

DN Reinemann, SR Norris, R Ohi, MJ Lang - Current Biology, 2018‏ - cell.com
A common mitotic defect observed in cancer cells that possess supernumerary (more than
two) centrosomes is multipolar spindle formation [1, 2]. Such structures are resolved into a …