Reactive oxygen or nitrogen species (ROS, RNS) and oxidative stress in the respiratory
system increase the production of mediators of pulmonary inflammation and initiate or …

Telomeres protect the integrity of information-carrying DNA by serving as caps on the
terminal portions of chromosomes. Telomere length decreases with aging, and this …

Purpose. Leukocyte telomere length (LTL) is an important biomarker of aging. The oxidative
balance score (OBS) is used to assess the oxidative stress‐related exposures of diet and …

Importance The causal direction and magnitude of the association between telomere length
and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility …

Early-life tobacco exposure serves as a non-negligible risk factor for aging-related diseases.
To understand the underlying mechanisms, we explored the associations of early-life …

Oxidative stress (OS), an imbalance between free radical generation and antioxidant
defence, is recognized as a key factor in the pathogenesis of adverse pregnancy outcomes …

Animal response to stressors such as harsh environmental conditions and demanding
biological processes requires energy generated through increased mitochondrial activity …

The attrition of telomeres, the ends of eukaryote chromosomes, is thought to play an
important role in cell deterioration with advancing age. The observed variation in telomere …

Non-alcoholic steatohepatitis (NASH) is characterised by hepatic steatosis and inflammation
and, in some patients, progressive fibrosis leading to cirrhosis. An understanding of the …

Inflammaging is characterized by the upregulation of the inflammatory response that occurs
with advancing age; its roots are strongly embedded in evolutionary theory. Inflammaging is …