Cognitive function during nicotine withdrawal: Implications for nicotine dependence treatment

RL Ashare, M Falcone, C Lerman - Neuropharmacology, 2014 - Elsevier
Nicotine withdrawal is associated with deficits in neurocognitive function including sustained
attention, working memory, and response inhibition. Several convergent lines of evidence …

Targeting GLP-1 receptors to reduce nicotine use disorder: preclinical and clinical evidence

RJ Herman, HD Schmidt - Physiology & behavior, 2024 - Elsevier
Nicotine use disorder (NUD) remains a leading cause of preventable death in the US
Unfortunately, current FDA-approved pharmacotherapies for smoking cessation have limited …

Liraglutide attenuates nicotine self-administration as well as nicotine seeking and hyperphagia during withdrawal in male and female rats

RJ Herman, MR Hayes, J Audrain-McGovern… - …, 2023 - Springer
Rationale Nicotine cessation is associated with increased consumption of highly palatable
foods and body weight gain in most smokers. Concerns about body weight gain are a major …

A novel dual agonist of glucagon-like peptide-1 receptors and neuropeptide Y2 receptors attenuates fentanyl taking and seeking in male rats

Y Zhang, S Rahematpura, KH Ragnini, A Moreno… - …, 2021 - Elsevier
There has been a dramatic increase in illicit fentanyl use in the United States over the last
decade. In 2018, more than 31,000 overdose deaths involved fentanyl or fentanyl analogs …

Neuropeptide systems and new treatments for nicotine addiction

AW Bruijnzeel - Psychopharmacology, 2017 - Springer
Rationale The mildly euphoric and cognitive enhancing effects of nicotine play a role in the
initiation of smoking, while dysphoria and anxiety associated with smoking cessation …

Paternal nicotine taking elicits heritable sex-specific phenotypes that are mediated by hippocampal Satb2

JJ Maurer, ME Wimmer, CA Turner, RJ Herman… - Molecular …, 2022 - nature.com
Nicotine intake, whether through tobacco smoking or e-cigarettes, remains a global health
concern. An emerging preclinical literature indicates that parental nicotine exposure …

Folic acid supplementation improved nicotine withdrawal-induced of memory loss via affecting oxidative status, inflammatory response, cholinergic activity, BDNF and …

SH Hosseini, ZS Khabbazhosseini, S Khatibi… - Neuroscience …, 2023 - Elsevier
Background The present study aimed to assess whether folic acid (FA) have potential to
prevent memory impairment caused by nicotine (Nico) withdrawal in adolescent male rats …

PYY3-36 infused systemically or directly into the VTA attenuates fentanyl seeking in male rats

A Caffrey, E Lavecchia, R Merkel, Y Zhang… - …, 2023 - Elsevier
More effective treatments for fentanyl use disorder are urgently needed. An emerging
literature indicates that glucagon-like peptide-1 receptor (GLP-1R) agonists attenuate …

Optimizing treatments for nicotine dependence by increasing cognitive performance during withdrawal

RL Ashare, HD Schmidt - Expert opinion on drug discovery, 2014 - Taylor & Francis
Introduction: Current FDA-approved smoking cessation pharmacotherapies have limited
efficacy and are associated with high rates of relapse. Therefore, there is a clear need to …

Neurobiological and neurophysiological mechanisms underlying nicotine seeking and smoking relapse

HD Schmidt, LE Rupprecht, NA Addy - Molecular neuropsychiatry, 2019 - karger.com
Tobacco-related morbidity and mortality continue to be a significant public health concern.
Unfortunately, current FDA-approved smoking cessation pharmacotherapies have limited …