MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas
B Oldrini, N Vaquero-Siguero, Q Mu, P Kroon… - Nature …, 2020 - nature.com
Temozolomide (TMZ) is an oral alkylating agent used for the treatment of glioblastoma and
is now becoming a chemotherapeutic option in patients diagnosed with high-risk low-grade …
is now becoming a chemotherapeutic option in patients diagnosed with high-risk low-grade …
Identifying predictors of glioma evolution from longitudinal sequencing
Clonal evolution drives cancer progression and therapeutic resistance. Recent studies have
revealed divergent longitudinal trajectories in gliomas, but early molecular features steering …
revealed divergent longitudinal trajectories in gliomas, but early molecular features steering …
[PDF][PDF] MYC amplification at diagnosis drives therapy-induced hypermutation of recurrent glioma
Abstract 1 Clonal evolution drives cancer progression and therapeutic resistance1, 2.
Recent 2 longitudinal analyses revealed divergent clonal dynamics in adult diffuse gliomas3 …
Recent 2 longitudinal analyses revealed divergent clonal dynamics in adult diffuse gliomas3 …
MYC amplification at diagnosis drives therapy-induced hypermutation of recurrent glioma
Clonal evolution drives cancer progression and therapeutic resistance 1-2. Recent
longitudinal analyses revealed divergent clonal dynamics in adult diffuse gliomas 3–11 …
longitudinal analyses revealed divergent clonal dynamics in adult diffuse gliomas 3–11 …
MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas.
N Vaquero-Siguero, Q Mu, P Kroon, Y Zhang… - 2020 - repisalud.isciii.es
Temozolomide (TMZ) is an oral alkylating agent used for the treatment of glioblastoma and
is now becoming a chemotherapeutic option in patients diagnosed with high-risk low-grade …
is now becoming a chemotherapeutic option in patients diagnosed with high-risk low-grade …
[HTML][HTML] Genetic and microenvironmental evolution of colorectal liver metastases under chemotherapy
Drug resistance limits the efficacy of chemotherapy for colorectal cancer liver metastasis
(CRLM). However, the evolution of CRLM during drug treatment remains poorly elucidated …
(CRLM). However, the evolution of CRLM during drug treatment remains poorly elucidated …