Central cholinergic systems and cognition
▪ Abstract The organization and possible functions of basal forebrain and pontine cholinergic
systems are reviewed. Whereas the basal forebrain cholinergic neuronal projections likely …
systems are reviewed. Whereas the basal forebrain cholinergic neuronal projections likely …
The unilateral 6-hydroxydopamine lesion model in behavioral brain research. Analysis of functional deficits, recovery and treatments
RKW Schwarting, JP Huston - Progress in neurobiology, 1996 - Elsevier
Lesions with the neurotoxin 6-hydroxydopamine (6-OHDA) have provided an important tool
to study dopamine neurons in the brain. The most common version of such lesions is the …
to study dopamine neurons in the brain. The most common version of such lesions is the …
Multipotent neural cell lines can engraft and participate in development of mouse cerebellum
EY Snyder, DL Deitcher, C Walsh, S Arnold-Aldea… - Cell, 1992 - cell.com
Multipotent neural cell lines were generated via retrovirus-mediated v-myc transfer into
murine cerebellar progenitor cells. When transplanted back into the cerebellum of newborn …
murine cerebellar progenitor cells. When transplanted back into the cerebellum of newborn …
Stem cell‐based cell therapy in neurological diseases: a review
SU Kim, J De Vellis - Journal of neuroscience research, 2009 - Wiley Online Library
Human neurological disorders such as Parkinson's disease, Huntington's disease,
amyotrophic lateral sclerosis (ALS), Alzheimer's disease, multiple sclerosis (MS), stroke, and …
amyotrophic lateral sclerosis (ALS), Alzheimer's disease, multiple sclerosis (MS), stroke, and …
Prospects for new restorative and neuroprotective treatments in Parkinson's disease
SB Dunnett, A Björklund - Nature, 1999 - nature.com
The degeneration of forebrain dopamine systems in Parkinson's disease has been an
effective target for pharmaceutical research over the past four decades. However, although …
effective target for pharmaceutical research over the past four decades. However, although …
Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats
In vitro expansion of central nervous system (CNS) precursors might overcome the limited
availability of dopaminergic neurons in transplantation for Parkinson's disease, but …
availability of dopaminergic neurons in transplantation for Parkinson's disease, but …
Tyrosine hydroxylase and Parkinson's disease
J Haavik, K Toska - Molecular neurobiology, 1998 - Springer
A consistent neurochemical abnormality in Parkinson's disease (PD) is degeneration of
dopaminergic neurons in substantia nigra, leading to a reduction of striatal dopamine (DA) …
dopaminergic neurons in substantia nigra, leading to a reduction of striatal dopamine (DA) …
Neural stem cell‐based treatment for neurodegenerative diseases
Human neurodegenrative diseases such as P arkinson's disease (PD), H untington's
disease (HD), amyotrophic lateral sclerosis (ALS) and A lzheimer's disease (AD) are caused …
disease (HD), amyotrophic lateral sclerosis (ALS) and A lzheimer's disease (AD) are caused …
Human neural stem cells genetically modified for brain repair in neurological disorders
SU Kim - Neuropathology, 2004 - Wiley Online Library
Existence of multipotent neural stem cells (NSC) has been known in develo** or adult
mammalian CNS, including humans. NSC have the capacity to grow indefinitely and have …
mammalian CNS, including humans. NSC have the capacity to grow indefinitely and have …
A synopsis on the role of tyrosine hydroxylase in Parkinson's disease
Parkinson's disease (PD) is a common chronic progressive neurodegenerative disorder in
elderly people. A consistent neurochemical abnormality in PD is degeneration of …
elderly people. A consistent neurochemical abnormality in PD is degeneration of …