Matrine is an alkaloid extracted from traditional Chinese herbs including Sophora
flavescentis, Sophora alopecuroides, Sophora root, etc. It has the dual advantages of …

Multiple sclerosis (MS) is an inflammatory and neurodegenerative disease that commonly
results in nontraumatic disability in young adults. The characteristic pathological hallmark of …

Recurrent spontaneous abortion (RSA) is a common complication of pregnancy that affects
the physical and mental health of pregnant women, and approximately 50% of the …

High-mobility group box-1 (HMGB1) is a nuclear protein associated with early inflammatory
changes upon extracellular secretion expressed in various cells, including neurons and …

High mobility group box 1 (HMGB1) is a ubiquitous and highly conserved non-histone DNA-
binding protein with different biological functions according to its subcellular localization. It is …

Hypoxia stabilizes hypoxia-inducible factors (HIFs), facilitating adaptation to hypoxic
conditions. Appropriate hypoxia is pivotal for neurovascular regeneration and immune cell …

Multiple sclerosis (MS) is a disabling neurodegenerative disease that causes demyelination
and axonal degeneration of the central nervous system. Current treatments are partially …

Ferroptosis, distinct from necrosis, autophagy and apoptosis, is a unique form of regulated
cell death, and is a potential pathogenic mechanism of neuronal loss and defunction in …

Multiple sclerosis (MS) is a debilitating, inflammatory, and demyelinating disease of the
central nervous system influenced by environmental and genetic factors. Around 2.8 million …

The inflammatory microenvironment after acute myocardial infarction (MI) is a key limiting
factor in the clinical application of stem cell transplantation and paracrine exosome therapy …