The medicinal panorama of benzimidazoles and their scaffolds as anticancer and antithrombotic agents: A review

PKB Chalkappa, S Aralihalli, M Sudileti… - Archiv der …, 2023 - Wiley Online Library
Nitrogen‐containing heterocyclic scaffolds have become a prospective pharmacophore with
therapeutic importance due to their biological similarities with natural and synthetic drugs …

α-Hydroxyphosphonates as versatile starting materials

Z Rádai - Phosphorus, Sulfur, and Silicon and the Related …, 2019 - Taylor & Francis
Abstract α-Hydroxyphosphonates constitute a class of organophosphorus compounds
famous for their bioactive properties. α-Hydroxyphosphonates may easily be functionalized …

Synthesis of bis (indolyl) methanes using hyper-cross-linked polyaromatic spheres decorated with bromomethyl groups as efficient and recyclable catalysts

RMN Kalla, SC Hong, I Kim - ACS omega, 2018 - ACS Publications
Highly uniform and hyper-cross-linked polyphenanthrene and polypyrene microspheres
were synthesized by Friedel–Crafts bromomethylation of phenanthrene (Phn) and pyrene …

Furan α-acetoxy methylphosphonates: Design and synthesis, in vitro antibacterial and antifungal activities, DFT, topology exploration (ELF, LOL, RDG) and molecular …

SG Lakoud, N Touil, H Bouraoui, F Hamoud… - Journal of Molecular …, 2025 - Elsevier
The addition of a furan moiety to methylphosphonate can lead to molecules possessing
strongest antibacterial and antifungal properties. In this work, novel furan α-acetoxy …

Tetrabutylammonium hydroxide (TBAH) ionic liquid for the sustainable and efficient production of α-hydroxyphosphonates

RMN Kalla, J Lee - Synthetic Communications, 2024 - Taylor & Francis
Ionic liquids were known as eco-solvents/catalysts, encourages the clean
hydrophosphonylation of aldehydes to produce structurally various α-hydroxyphosphonates …

Synthesis and anticancer cytotoxicity with structural context of an α-hydroxyphosphonate based compound library derived from substituted benzaldehydes

Z Rádai, T Windt, V Nagy, A Füredi, NZ Kiss… - New Journal of …, 2019 - pubs.rsc.org
We synthesized substituted benzaldehyde derived α-hydroxyphosphonates (αOHP), α-
hydroxyphosphonic acids (αOHPA) and α-phosphinoyloxyphosphonates (αOPP) and …

Catalyst‐Free Synthesis of Xanthene and Pyrimidine‐Fused Heterocyclic Derivatives at Water‐Ethanol Medium and Their Antioxidant Properties

RM Naidu Kalla, RS Karunakaran, M Balaji… - …, 2019 - Wiley Online Library
Abstract Water‐ethanol (1: 1 v/v) reaction medium has been demonstrated to be an efficient
system for the catalyst‐free synthesis of biologically potent xanthene and pyrimidine‐fused …

Catalyst-free ultrasonic-promoted multicomponent synthesis of tertiary α-amino phosphonates

RMN Kalla, J Bae, I Kim - New Journal of Chemistry, 2017 - pubs.rsc.org
A highly efficient and green protocol has been developed for the synthesis of a new class of
tertiary α-amino phosphonates (TAPs) via the Kabachnik–Fields reactions of substituted …

Sulfated choline ionic liquid-catalyzed acetamide synthesis by grindstone method

RMN Kalla, J Lim, J Bae, I Kim - Tetrahedron Letters, 2017 - Elsevier
Sulfated choline ionic liquid (SCIL) has been found to be an efficient solid acid IL catalyst for
the protection of amine groups with acetic anhydride under solvent-free grindstone …

Biocatalytic promiscuity of lipases in carbon‐phosphorus bond formation

D Koszelewski, R Ostaszewski - ChemCatChem, 2019 - Wiley Online Library
A promiscuous lipase‐catalyzed carbon‐phosphorus bond formation is presented. The
developed enzymatic Pudovik‐Abramov reaction of various aromatic and aliphatic …