Purpose This paper reviews 10 principles of experience-dependent neural plasticity and
considerations in applying them to the damaged brain. Method Neuroscience research …

Spinal cord injury (SCI) can lead to paraplegia or quadriplegia. Although there are no fully
restorative treatments for SCI, various rehabilitative, cellular and molecular therapies have …

Restoration of human brain function after injury is a signal challenge for translational
neuroscience. Rodent stroke recovery studies identify an optimal or sensitive period for …

Objective: To review the underlying pathophysiologic processes of concussive brain injury
and relate these neurometabolic changes to clinical sports-related issues such as injury to …

We have reviewed a battery of useful tests for evaluating sensorimotor function and plasticity
acutely and chronically in unilateral rat models of central nervous system injury. These tests …

Objective: Our prespecified dose-response analyses of A Very Early Rehabilitation Trial
(AVERT) aim to provide practical guidance for clinicians on the timing, frequency, and …

Neuronal connections and cortical maps are continuously remodeled by our experience.
Knowledge of the potential capabilityof the brain to compensate for lesions is a prerequisite …

Background Mobilising patients early after stroke [early mobilisation (EM)] is thought to
contribute to the beneficial effects of stroke unit care but it is poorly defined and lacks direct …

An account of the neurobiology of motor recovery in the arm and hand after stroke by two
experts in the field. Stroke is a leading cause of disability in adults and recovery is often …

Environmental enrichment (EE) has been widely used as a means to enhance brain
plasticity mechanisms (eg, increased dendritic branching, synaptogenesis, etc.) and improve …