Liquid biomolecular condensates and viral lifecycles: review and perspectives

TA Etibor, Y Yamauchi, MJ Amorim - Viruses, 2021 - mdpi.com
Viruses are highly dependent on the host they infect. Their dependence triggers processes
of virus–host co-adaptation, enabling viruses to explore host resources whilst esca** …

Influenza virus morphogenesis and budding

DP Nayak, RA Balogun, H Yamada, ZH Zhou… - Virus research, 2009 - Elsevier
Influenza viruses are enveloped, negative stranded, segmented RNA viruses belonging to
Orthomyxoviridae family. Each virion consists of three major sub-viral components, namely …

An overlap** protein-coding region in influenza A virus segment 3 modulates the host response

BW Jagger, HM Wise, JC Kash, KA Walters, NM Wills… - Science, 2012 - science.org
Influenza A virus (IAV) infection leads to variable and imperfectly understood pathogenicity.
We report that segment 3 of the virus contains a second open reading frame (“X-ORF”) …

A Rab11-and microtubule-dependent mechanism for cytoplasmic transport of influenza A virus viral RNA

MJ Amorim, EA Bruce, EKC Read, A Foeglein… - Journal of …, 2011 - Am Soc Microbiol
The viral RNA (vRNA) genome of influenza A virus is replicated in the nucleus, exported to
the cytoplasm as ribonucleoproteins (RNPs), and trafficked to the plasma membrane …

Emerging roles for the influenza A virus nuclear export protein (NEP)

D Paterson, E Fodor - PLoS pathogens, 2012 - journals.plos.org
Influenza virus is a major human and animal pathogen causing seasonal epidemics and
occasional pandemics in the human population that are associated with significant morbidity …

Influenza A virus NS1 protein binds p85β and activates phosphatidylinositol-3-kinase signaling

BG Hale, D Jackson, YH Chen… - Proceedings of the …, 2006 - National Acad Sciences
Influenza A virus NS1 is a multifunctional protein, and in virus-infected cells NS1 modulates
a number of host-cell processes by interacting with cellular factors. Here, we report that NS1 …

[HTML][HTML] Influenza virus assembly and budding in raft-derived microdomains: a quantitative analysis of the surface distribution of HA, NA and M2 proteins

GP Leser, RA Lamb - Virology, 2005 - Elsevier
Influenza virus hemagglutinin (HA) and neuraminidase (NA) are known to associate with
lipid rafts, membrane microdomains comprised of densely packed cholesterol and …

The Rab11 pathway is required for influenza A virus budding and filament formation

EA Bruce, P Digard, AD Stuart - Journal of virology, 2010 - Am Soc Microbiol
Influenza A virus buds through the apical plasma membrane, forming enveloped virus
particles that can take the shape of pleomorphic spheres or vastly elongated filaments. For …

The lipid raft hypothesis revisited–New insights on raft composition and function from super‐resolution fluorescence microscopy

DM Owen, A Magenau, D Williamson, K Gaus - Bioessays, 2012 - Wiley Online Library
Recently developed super‐resolution microscopy techniques are changing our
understanding of lipid rafts and membrane organisation in general. The lipid raft hypothesis …

Identification of the domains of the influenza A virus M1 matrix protein required for NP binding, oligomerization and incorporation into virions

SL Noton, E Medcalf, D Fisher… - Journal of General …, 2007 - microbiologyresearch.org
The matrix (M1) protein of influenza A virus is a multifunctional protein that plays essential
structural and functional roles in the virus life cycle. It drives virus budding and is the major …