Acute lymphoblastic leukaemia

L Pagliaro, SJ Chen, D Herranz, C Mecucci… - Nature Reviews …, 2024 - nature.com
Acute lymphoblastic leukaemia (ALL) is a haematological malignancy characterized by the
uncontrolled proliferation of immature lymphoid cells. Over past decades, significant …

International Consensus Classification of acute lymphoblastic leukemia/lymphoma

AS Duffield, CG Mullighan, MJ Borowitz - Virchows Archiv, 2023 - Springer
Abstract The updated International Consensus Classification (ICC) of B-acute lymphoblastic
leukemia (B-ALL) and T-acute lymphoblastic leukemia (T-ALL) includes both revisions to …

Acute lymphoblastic leukemia: a comprehensive review and 2017 update

T Terwilliger, M Abdul-Hay - Blood cancer journal, 2017 - nature.com
Acute lymphoblastic leukemia (ALL) is the second most common acute leukemia in adults,
with an incidence of over 6500 cases per year in the United States alone. The hallmark of …

Genetic basis of acute lymphoblastic leukemia

I Iacobucci, CG Mullighan - Journal of clinical oncology, 2017 - ascopubs.org
Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, and despite cure
rates exceeding 90% in children, it remains an important cause of morbidity and mortality in …

Childhood acute lymphoblastic leukemia: progress through collaboration

CH Pui, JJ Yang, SP Hunger, R Pieters… - Journal of Clinical …, 2015 - ascopubs.org
Purpose To review the impact of collaborative studies on advances in the biology and
treatment of acute lymphoblastic leukemia (ALL) in children and adolescents. Methods A …

Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia

KG Roberts, Y Li, D Payne-Turner… - New England journal …, 2014 - Mass Medical Soc
Background Philadelphia chromosome–like acute lymphoblastic leukemia (Ph-like ALL) is
characterized by a gene-expression profile similar to that of BCR–ABL1–positive ALL …

Treatment and biology of pediatric acute lymphoblastic leukemia

M Kato, A Manabe - Pediatrics International, 2018 - Wiley Online Library
Acute lymphoblastic leukemia (ALL) is the most common pediatric malignancy. In the past
ALL was intractable but now the survival probability is as high as 80–90%. Improved …

Ph-like acute lymphoblastic leukemia: a high-risk subtype in adults

N Jain, KG Roberts, E Jabbour, K Patel… - Blood, The Journal …, 2017 - ashpublications.org
Philadelphia chromosome (Ph)-like acute lymphoblastic leukemia (ALL) is a high-risk
subtype of ALL in children. There are conflicting data on the incidence and prognosis of Ph …

Transcriptional landscape of B cell precursor acute lymphoblastic leukemia based on an international study of 1,223 cases

JF Li, YT Dai, H Lilljebjörn, SH Shen, BW Cui… - Proceedings of the …, 2018 - pnas.org
Most B cell precursor acute lymphoblastic leukemia (BCP ALL) can be classified into known
major genetic subtypes, while a substantial proportion of BCP ALL remains poorly …

Acute lymphoblastic leukaemia

H Inaba, M Greaves, CG Mullighan - The Lancet, 2013 - thelancet.com
Acute lymphoblastic leukaemia occurs in both children and adults but its incidence peaks
between 2 and 5 years of age. Causation is multifactorial and exogenous or endogenous …