[PDF][PDF] Treatment of renal cell carcinoma: current status and future directions

PC Barata, BI Rini - CA: a cancer journal for clinicians, 2017 - researchgate.net
Over the past 12 years, medical treatment for renal cell carcinoma (RCC) has transitioned
from a nonspecific immune approach (in the cytokine era), to targeted therapy against …

Kidney cancer, version 3.2022, NCCN clinical practice guidelines in oncology

RJ Motzer, E Jonasch, N Agarwal, A Alva… - Journal of the National …, 2022 - jnccn.org
The NCCN Guidelines for Kidney Cancer focus on the screening, diagnosis, staging,
treatment, and management of renal cell carcinoma (RCC). Patients with relapsed or stage …

Systematic review of the role of cytoreductive nephrectomy in the targeted therapy era and beyond: an individualized approach to metastatic renal cell carcinoma

B Bhindi, EJ Abel, L Albiges, K Bensalah, SA Boorjian… - European urology, 2019 - Elsevier
Context The role of cytoreductive nephrectomy (CN) in the management of metastatic renal
cell carcinoma (mRCC) in the targeted therapy (TT) era is controversial. Objective To assess …

Management of metastatic clear cell renal cell carcinoma: ASCO guideline

WK Rathmell, RB Rumble… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE To provide recommendations for the management of patients with metastatic
clear cell renal cell carcinoma (ccRCC). METHODS An Expert Panel conducted a systematic …

Kidney cancer, version 2.2017, NCCN clinical practice guidelines in oncology

RJ Motzer, E Jonasch, N Agarwal, S Bhayani… - Journal of the National …, 2017 - jnccn.org
The NCCN Guidelines for Kidney Cancer provide multidisciplinary recommendations for the
clinical management of patients with clear cell and non–clear cell renal carcinoma. These …

Cytoreductive nephrectomy in patients with synchronous metastases from renal cell carcinoma: results from the International Metastatic Renal Cell Carcinoma …

DYC Heng, JC Wells, BI Rini, B Beuselinck, JL Lee… - European urology, 2014 - Elsevier
Background The benefit of cytoreductive nephrectomy (CN) for overall survival (OS) is
unclear in patients with synchronous metastatic renal cell carcinoma (mRCC) in the era of …

Survival analyses of patients with metastatic renal cancer treated with targeted therapy with or without cytoreductive nephrectomy: a national cancer data base study

N Hanna, M Sun, CP Meyer, PL Nguyen… - Journal of Clinical …, 2016 - ascopubs.org
Purpose The role of cytoreductive nephrectomy (CN) in metastatic renal cell carcinoma
(mRCC) has become unclear since the introduction of targeted therapies (TT). We sought to …

Complementary roles of surgery and systemic treatment in clear cell renal cell carcinoma

A Ingels, R Campi, U Capitanio, D Amparore… - Nature Reviews …, 2022 - nature.com
Standard-of-care management of renal cell carcinoma (RCC) indisputably relies on surgery
for low-risk localized tumours and systemic treatment for poor-prognosis metastatic disease …

Upfront cytoreductive nephrectomy for metastatic renal cell carcinoma treated with immune checkpoint inhibitors or targeted therapy: an observational study from the …

Z Bakouny, T El Zarif, S Dudani, JC Wells, CL Gan… - European urology, 2023 - Elsevier
Background The role of upfront cytoreductive nephrectomy (CN) for metastatic renal cell
carcinoma (mRCC) in the era of immune checkpoint inhibitors is unclear. Objective To …

Landmarks in the diagnosis and treatment of renal cell carcinoma

JR Bhatt, A Finelli - Nature Reviews Urology, 2014 - nature.com
The most common renal cancer is renal cell carcinoma (RCC), which arises from the renal
parenchyma. The global incidence of RCC has increased over the past two decades by 2 …