Liquid biopsies in cancer diagnosis, monitoring, and prognosis

G De Rubis, SR Krishnan, M Bebawy - Trends in pharmacological sciences, 2019 - cell.com
Liquid biopsies, comprising the noninvasive analysis of circulating tumor-derived material
(the 'tumor circulome'), represent an innovative tool in precision oncology to overcome …

miRNAS in cardiovascular diseases: potential biomarkers, therapeutic targets and challenges

S Zhou, J **, J Wang, Z Zhang, JH Freedman… - Acta Pharmacologica …, 2018 - nature.com
Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality in the
world. Although considerable progress has been made in the diagnosis, treatment and …

Clinical utility of circulating non-coding RNAs—an update

S Anfossi, A Babayan, K Pantel, GA Calin - Nature reviews Clinical …, 2018 - nature.com
Over the past decade, the amount of research and the number of publications on
associations between circulating small and long non-coding RNAs (ncRNAs) and cancer …

Novel diagnostic biomarkers in colorectal cancer

AL Zygulska, P Pierzchalski - International journal of molecular sciences, 2022 - mdpi.com
Colorectal cancer (CRC) is still a leading cause of cancer death worldwide. Less than half of
cases are diagnosed when the cancer is locally advanced. CRC is a heterogenous disease …

Data normalization strategies for microRNA quantification

H Schwarzenbach, AM Da Silva, G Calin… - Clinical …, 2015 - academic.oup.com
BACKGROUND Different technologies, such as quantitative real-time PCR or microarrays,
have been developed to measure microRNA (miRNA) expression levels. Quantification of …

[HTML][HTML] Extracellular/circulating microRNAs: release mechanisms, functions and challenges

MH Sohel - Achievements in the Life Sciences, 2016 - Elsevier
MicroRNAs (miRNAs) are endogenously initiated, small non-coding RNAs and typically
regulate the expression of mRNAs in post transcriptional level either via translational …

Integrated extracellular microRNA profiling for ovarian cancer screening

A Yokoi, J Matsuzaki, Y Yamamoto, Y Yoneoka… - Nature …, 2018 - nature.com
A major obstacle to improving prognoses in ovarian cancer is the lack of effective screening
methods for early detection. Circulating microRNAs (miRNAs) have been recognized as …

Circulating miRNA panels for specific and early detection in bladder cancer

W Usuba, F Urabe, Y Yamamoto, J Matsuzaki… - Cancer …, 2019 - Wiley Online Library
Bladder cancer is the 9th leading cause of cancer death worldwide. The major problem in
bladder cancer is primarily the high recurrence rate after drug treatment and resection …

Circulating miRNA analysis for cancer diagnostics and therapy

L Valihrach, P Androvic, M Kubista - Molecular Aspects of Medicine, 2020 - Elsevier
Successful treatment of cancer depends on early diagnosis and effective monitoring of
patients' response to therapy. Traditional tools based on tumor biopsies lack the sensitivity …

Liquid biopsies, novel approaches and future directions

A Armakolas, M Kotsari, J Koskinas - Cancers, 2023 - mdpi.com
Simple Summary The gold standard for detecting cancer and profiling tumors is tissue
biopsies. Despite this, tissue biopsies have been associated with many limitations leading to …