[HTML][HTML] Drug resistance and new therapies in colorectal cancer
Colorectal cancer (CRC) is often diagnosed at an advanced stage when tumor cell
dissemination has taken place. Chemo-and targeted therapies provide only a limited …
dissemination has taken place. Chemo-and targeted therapies provide only a limited …
The prognostic implications of tumor infiltrating lymphocytes in colorectal cancer: a systematic review and meta-analysis
Tumor-infiltrating lymphocytes (TILs) are an important histopathologic feature of colorectal
cancer that confer prognostic information. Previous clinical and epidemiologic studies have …
cancer that confer prognostic information. Previous clinical and epidemiologic studies have …
International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study
Background The estimation of risk of recurrence for patients with colon carcinoma must be
improved. A robust immune score quantification is needed to introduce immune parameters …
improved. A robust immune score quantification is needed to introduce immune parameters …
Multicenter international society for immunotherapy of cancer study of the consensus immunoscore for the prediction of survival and response to chemotherapy in …
PURPOSE The purpose of this study was to evaluate the prognostic value of Immunoscore
in patients with stage III colon cancer (CC) and to analyze its association with the effect of …
in patients with stage III colon cancer (CC) and to analyze its association with the effect of …
Genetic mechanisms of immune evasion in colorectal cancer
To understand the genetic drivers of immune recognition and evasion in colorectal cancer,
we analyzed 1,211 colorectal cancer primary tumor samples, including 179 classified as …
we analyzed 1,211 colorectal cancer primary tumor samples, including 179 classified as …
Genomic correlates of immune-cell infiltrates in colorectal carcinoma
Large-scale genomic characterization of tumors from prospective cohort studies may yield
new insights into cancer pathogenesis. We performed whole-exome sequencing of 619 …
new insights into cancer pathogenesis. We performed whole-exome sequencing of 619 …
Classifying cancers based on T-cell infiltration and PD-L1
Cancer immunotherapy may become a major treatment backbone in many cancers over the
next decade. There are numerous immune cell types found in cancers and many …
next decade. There are numerous immune cell types found in cancers and many …
Combination cancer immunotherapies tailored to the tumour microenvironment
Evidence suggests that cancer immunotherapy will be a major part of the combination
treatment plan for many patients with many cancer types in the near future. There are many …
treatment plan for many patients with many cancer types in the near future. There are many …
Cytokine‐and chemokine‐induced inflammatory colorectal tumor microenvironment: Emerging avenue for targeted therapy
Colorectal cancer (CRC) is a predominant life‐threatening cancer, with liver and peritoneal
metastases as the primary causes of death. Intestinal inflammation, a known CRC risk factor …
metastases as the primary causes of death. Intestinal inflammation, a known CRC risk factor …
Advances in immunotherapy for colorectal cancer: a review
G Golshani, Y Zhang - Therapeutic advances in …, 2020 - journals.sagepub.com
Immunotherapy is a new and exciting modality of cancer treatments. Its role in
gastrointestinal malignancies has been promising, especially in advanced disease …
gastrointestinal malignancies has been promising, especially in advanced disease …