Drug administration by inhalation is a well-established approach to treat respiratory and
systemic diseases. To deliver a drug into the lung dry powder inhalation (DPI) is an …

Used since ancient times especially for the local treatment of pulmonary diseases, lungs and
airways are a versatile target route for the administration of both local and systemic drugs …

Novel inhaled therapeutics including antibiotics, vaccines and anti-hypertensives, have led
to innovations in designing suitable delivery systems. These emerging design technologies …

The dry powder inhaler (DPI) stands out as a highly patient-friendly and effective pulmonary
formulation, surpassing traditional and other pulmonary dosage forms in certain disease …

The potential of fine excipient materials to improve the aerodynamic performance of carrier-
based dry powder inhalation (DPI) formulations is well acknowledged but not fully …

For about 15 years the performance of dry powder inhalers (DPIs) has been numerically
analysed through CFD (computational fluid dynamics) approaches with the objective of …

Introduction: The number of pulmonary diseases that are effectively treated by aerosolized
medicine continues to grow. Areas covered: These diseases include chronic obstructive …

Regulatory science for generic dry powder inhalers (DPIs) in the United States (US) has
evolved over the last decade. In 2013, the US Food and Drug Administration (FDA) …

Introduction: Computational fluid dynamics (CFD) has recently seen increased use in the
design of pharmaceutical inhalers. The use of CFD in the design of inhalers is made difficult …

This study investigated the effect of modifying the design of the Cyclohaler on its
aerosolization performance and comparability to the HandiHaler at multiple flow rates. The …