The vagus nerve is an indispensable body-brain connection that controls vital aspects of
autonomic physiology like breathing, heart rate, blood pressure, and gut motility, reflexes …

Here we discuss the neuroanatomy of extrinsic gastrointestinal (GI) afferent neurones, the
relationship between structure and function and the role of afferents in disease. Three …

Although the gastric tension receptor has been characterized behaviorally and
electrophysiologically quite well, its location and structure remains elusive. Therefore, the …

The gastrointestinal (GI) tract must balance ostensibly opposite functions. On the one hand,
it must undertake the process of digestion and absorption of nutrients. At the same time, the …

Nonerosive reflux disease is defined as the presence of typical symptoms of
gastroesophageal reflux disease caused by intraesophageal acid in the absence of visible …

Satiation for food comprises the physiological processes that result in the termination of
eating. Satiation is evoked by physical and chemical qualities of ingested food, which trigger …

1 Distension‐sensitive vagal afferent fibres from the cardiac region of the guinea‐pig
stomach were recorded extracellularly, then filled with biotinamide, using an anterograde …

Electrophysiological and morphological analyses of vagal mechanoreceptors in the gut wall
suggest conflicting conclusions. Electrophysiology has distinguished a single general class …

Background & Aims: Chronic tissue injury in the esophagus associated with
gastroesophageal reflux disease may result in sensitization of afferent pathways mediating …

Despite their seemingly elementary roles, the colon and rectum undertake a variety of key
processes to ensure our overall wellbeing. Such processes are coordinated by the …