Polymer–drug conjugate therapeutics: advances, insights and prospects
Polymer–drug conjugates have long been a mainstay of the drug delivery field, with several
conjugates successfully translated into clinical practice. The conjugation of therapeutic …
conjugates successfully translated into clinical practice. The conjugation of therapeutic …
Polyethylene glycol (PEG): The nature, immunogenicity, and role in the hypersensitivity of PEGylated products
Polyethylene glycol (PEG) is a versatile polymer that is widely used as an additive in foods
and cosmetics, and as a carrier in PEGylated therapeutics. Even though PEG is thought to …
and cosmetics, and as a carrier in PEGylated therapeutics. Even though PEG is thought to …
PEGylated therapeutics in the clinic
The covalent attachment of polyethylene glycol (PEG) to therapeutic agents, termed
PEGylation, is a well‐established and clinically proven drug delivery approach to improve …
PEGylation, is a well‐established and clinically proven drug delivery approach to improve …
In silico study the inhibition of angiotensin converting enzyme 2 receptor of COVID-19 by Ammoides verticillata components harvested from Western Algeria
I Abdelli, F Hassani, S Bekkel Brikci… - Journal of Biomolecular …, 2021 - Taylor & Francis
The objective of this present study is to focus on the in silico study to screen for an
alternative drug that can block the activity of the angiotensin converting enzyme 2 (ACE2) as …
alternative drug that can block the activity of the angiotensin converting enzyme 2 (ACE2) as …
[HTML][HTML] Hemophilia therapy: the future has begun
PM Mannucci - Haematologica, 2020 - ncbi.nlm.nih.gov
The success story of hemophilia care first began in the 1970s, when the availability of
plasma-derived concentrates of coagulation factor VIII (FVIII) and factor IX (FIX) provided …
plasma-derived concentrates of coagulation factor VIII (FVIII) and factor IX (FIX) provided …
Pharmapolymers in the 21st century: Synthetic polymers in drug delivery applications
The administration of drugs, as a main challenge of pharmaceutical and medicinal
applications, has certainly benefited from the application of synthetic polymers. However …
applications, has certainly benefited from the application of synthetic polymers. However …
Chemical and physical Chitosan modification for designing enzymatic industrial biocatalysts: How to choose the best strategy?
YL Nunes, FL de Menezes, IG de Sousa… - International Journal of …, 2021 - Elsevier
Chitosan is one of the most abundant natural polymer worldwide, and due to its inherent
characteristics, its use in industrial processes has been extensively explored. Because it is …
characteristics, its use in industrial processes has been extensively explored. Because it is …
Drying technologies for the stability and bioavailability of biopharmaceuticals
F Emami, A Vatanara, EJ Park, DH Na - Pharmaceutics, 2018 - mdpi.com
Solid dosage forms of biopharmaceuticals such as therapeutic proteins could provide
enhanced bioavailability, improved storage stability, as well as expanded alternatives to …
enhanced bioavailability, improved storage stability, as well as expanded alternatives to …
[HTML][HTML] Hemophilia treatment innovation: 50 years of progress and more to come
PM Mannucci - Journal of Thrombosis and Haemostasis, 2023 - Elsevier
With the goal of emphasizing the striking advances that materialized in hemophilia care
particularly in the last 10 years, the progress of knowledge that started from the 1970s will …
particularly in the last 10 years, the progress of knowledge that started from the 1970s will …
Current strategies in extending half-lives of therapeutic proteins
Macromolecular protein and peptide therapeutics have been proven to be effective in
treating critical human diseases precisely. Thanks to biotechnological advancement, a huge …
treating critical human diseases precisely. Thanks to biotechnological advancement, a huge …