Genetics of human brain development

Y Zhou, H Song, G Ming - Nature Reviews Genetics, 2024‏ - nature.com
Brain development in humans is achieved through precise spatiotemporal genetic control,
the mechanisms of which remain largely elusive. Recently, integration of technological …

Interneuron cell types are fit to function

A Kepecs, G Fishell - Nature, 2014‏ - nature.com
Understanding brain circuits begins with an appreciation of their component parts—the cells.
Although GABAergic interneurons are a minority population within the brain, they are crucial …

Developmental diversification of cortical inhibitory interneurons

C Mayer, C Hafemeister, RC Bandler, R Machold… - Nature, 2018‏ - nature.com
Diverse subsets of cortical interneurons have vital roles in higher-order brain functions. To
investigate how this diversity is generated, here we used single-cell RNA sequencing to …

Neuregulin-ERBB signaling in the nervous system and neuropsychiatric diseases

L Mei, KA Nave - Neuron, 2014‏ - cell.com
Neuregulins (NRGs) comprise a large family of growth factors that stimulate ERBB receptor
tyrosine kinases. NRGs and their receptors, ERBBs, have been identified as susceptibility …

The basics of brain development

J Stiles, TL Jernigan - Neuropsychology review, 2010‏ - Springer
Over the past several decades, significant advances have been made in our understanding
of the basic stages and mechanisms of mammalian brain development. Studies elucidating …

Competing waves of oligodendrocytes in the forebrain and postnatal elimination of an embryonic lineage

N Kessaris, M Fogarty, P Iannarelli, M Grist… - Nature …, 2006‏ - nature.com
The developmental origin of oligodendrocyte progenitors (OLPs) in the forebrain has been
controversial. We now show, by Cre-lox fate map** in transgenic mice, that the first OLPs …

[ספר][B] Cortex and mind: Unifying cognition

JM Fuster - 2005‏ - books.google.com
This book presents a unique synthesis of the current neuroscience of cognition by one of the
world's authorities in the field. The guiding principle to this synthesis is the tenet that the …

Histology atlas of the develo** prenatal and postnatal mouse central nervous system, with emphasis on prenatal days E7. 5 to E18. 5

VS Chen, JP Morrison, MF Southwell… - Toxicologic …, 2017‏ - journals.sagepub.com
Evaluation of the central nervous system (CNS) in the develo** mouse presents unique
challenges, given the complexity of ontogenesis, marked structural reorganization over very …

Genetic fate map** reveals that the caudal ganglionic eminence produces a large and diverse population of superficial cortical interneurons

G Miyoshi, J Hjerling-Leffler, T Karayannis… - Journal of …, 2010‏ - jneurosci.org
By combining an inducible genetic fate map** strategy with electrophysiological analysis,
we have systematically characterized the populations of cortical GABAergic interneurons …

Cell migration in the forebrain

O Marín, JLR Rubenstein - Annual review of neuroscience, 2003‏ - annualreviews.org
▪ Abstract The forebrain comprises an intricate set of structures that are required for some of
the most complex and evolved functions of the mammalian brain. As a reflection of its …