HLA and pharmacogenetics of drug hypersensitivity

R Pavlos, S Mallal, E Phillips - Pharmacogenomics, 2012 - Taylor & Francis
Immunologically mediated drug reactions have been traditionally classified as unpredictable
based on the fact that they cannot be predicted strictly on the pharmacological action of the …

Pharmacogenetics of antiepileptic drug-induced hypersensitivity

KM Bloch, GJ Sills, M Pirmohamed… - Pharmacogenomics, 2014 - Taylor & Francis
Antiepileptic drugs can induce potentially life-threatening hypersensitivity reactions such as
Stevens–Johnson syndrome at a frequency of one in 10,000 to one in 1000 treated patients …

Lamotrigine induced DIHS/DRESS: Manifestations, treatment, and outcome in 57 patients

X Wang, H Wang, X Zhang, S Yu, X Huang… - Clinical Neurology and …, 2015 - Elsevier
Objective To evaluate the clinical features, course, response to treatment, and outcome of
lamotrigine induced drug-induced hypersensitivity syndrome (DIHS) or drug reaction with …

An update on the immunological, metabolic and genetic mechanisms in drug hypersensitivity reactions

C Mayorga, MI Montañez… - Current …, 2019 - ingentaconnect.com
Drug hypersensitivity reactions (DHRs) represent a major burden on the healthcare system
since their diagnostic and management are complex. As they can be influenced by …

Antiepileptics

B Spoelhof, L Frendak, LR Lara - Side Effects of Drugs Annual, 2015 - Elsevier
Abstract The Side Effects of Drugs Annuals is a series of volumes in which the adverse
effects and reactions of medications are analyzed. The series supplements the contents of …