[HTML][HTML] Nanostructured lipid carriers (NLCs) as drug delivery platform: Advances in formulation and delivery strategies

M Elmowafy, MM Al-Sanea - Saudi Pharmaceutical Journal, 2021 - Elsevier
NLCs have provoked the incessant impulsion for the development of safe and valuable drug
delivery systems owing to their exceptional physicochemical and then biocompatible …

[HTML][HTML] Nanostructured lipid carriers and their potential applications for versatile drug delivery via oral administration

VN Thuy, TV Van, AH Dao, BJ Lee - OpenNano, 2022 - Elsevier
Enteral administration is the most convenient route despite the gastrointestinal physiological
barriers. Nanostructured lipid carriers (NLCs) have emerged as a promising strategy for …

Nanoparticles for oral delivery: targeted therapy for inflammatory bowel disease

D Li, M Yang, H Xu, M Zhu, Y Zhang, C Tian… - Journal of Materials …, 2022 - pubs.rsc.org
As a group of chronic and idiopathic gastrointestinal (GI) disorders, inflammatory bowel
disease (IBD) is characterized by recurrent intestinal mucosal inflammation. Oral …

Using the quality by design (QbD) approach to optimize formulations of lipid nanoparticles and nanoemulsions: A review

S Cunha, CP Costa, JN Moreira, JMS Lobo… - … , Biology and Medicine, 2020 - Elsevier
Abstract Quality-by-design (QbD) approach has been applied to optimize lipid-based
nanosystems formulations, including solid lipid nanoparticles (SLN), nanostructured lipid …

Enhanced oral bioavailability of nintedanib esylate with nanostructured lipid carriers by lymphatic targeting: In vitro, cell line and in vivo evaluation

P Patel, M Patel - European Journal of Pharmaceutical Sciences, 2021 - Elsevier
The present research work was aimed to explore the ability of nanostructured lipid carriers
(NLCs) to improve oral bioavailability of Nintedanib esylate (NE) via lymphatic uptake. The …

Formulation, optimization, and characterization of rifampicin-loaded solid lipid nanoparticles for the treatment of tuberculosis

NV Chokshi, HN Khatri, MM Patel - Drug development and …, 2018 - Taylor & Francis
Mycobacterium tuberculosis, being the causative infectious agent, is the leading cause of
death worldwide amongst the infectious disease. The low bioavailability of rifampicin (RIF) …

Nanostructured lipid carriers to enhance the bioavailability and solubility of ranolazine: Statistical optimization and pharmacological evaluations

A Unnisa, AK Chettupalli, RS Alazragi, W Alelwani… - Pharmaceuticals, 2023 - mdpi.com
Chronic stable angina pectoris is the primary indication for ranolazine (RZ), an anti-anginal
drug. The drug has an anti-ischemic action that is unaffected by either blood pressure or …

Enteric-coated strategies in colorectal cancer nanoparticle drug delivery system

N Wathoni, AN Nguyen, A Rusdin… - Drug design …, 2020 - Taylor & Francis
Colorectal cancer is one of the most common cancer diseases with the increase of cases
prevalence> 5% every year. Multidrug resistance mechanisms and non-localized therapy …

[HTML][HTML] Development and Evaluation of Docetaxel-Loaded Nanostructured Lipid Carriers for Skin Cancer Therapy

FI Cocoș, V Anuța, L Popa, MV Ghica, MA Nica… - Pharmaceutics, 2024 - mdpi.com
This study focuses on the design, characterization, and optimization of nanostructured lipid
carriers (NLCs) loaded with docetaxel for the treatment of skin cancer. Employing a …

Fabrication, optimization, and in vitro evaluation of docetaxel-loaded nanostructured lipid carriers for improved anticancer activity

P Mathur, S Sharma, S Rawal, B Patel… - Journal of liposome …, 2020 - Taylor & Francis
Lung cancer is the leading cause of cancer-related deaths in both men and women
worldwide. It is the leading cancer killer in both men and women in every Ethnic Group. A …