Almost 20 years have passed since the first reference genome assemblies were published
for Plasmodium falciparum, the deadliest malaria parasite, and Anopheles gambiae, the …

Plasmodium falciparum and Plasmodium vivax account for more than 95% of all human
malaria infections, and thus pose a serious public health challenge. To control and …

Next generation sequencing (NGS) combined with bioinformatics has successfully been
used in a vast array of analyses for infectious disease research of public health relevance …

Background Rodent malaria parasites (RMP) are used extensively as models of human
malaria. Draft RMP genomes have been published for Plasmodium yoelii, P. berghei ANKA …

Protozoan Plasmodium parasites are the causative agents of malaria, a deadly disease that
continues to afflict hundreds of millions of people every year. Infections with malaria …

Plasmodium vivax is the leading cause of human malaria in Asia and Latin America but is
absent from most of central Africa due to the near fixation of a mutation that inhibits the …

Plasmodium vivax is a major public health burden, responsible for the majority of malaria
infections outside Africa. We explored the impact of demographic history and selective …

The widespread distribution and relapsing nature of Plasmodium vivax infection present
major challenges for the elimination of malaria. To characterize the genetic diversity of this …

African apes harbour at least six Plasmodium species of the subgenus Laverania, one of
which gave rise to human Plasmodium falciparum. Here we use a selective amplification …

Coevolution of humans and malaria parasites has generated an intricate balance between
the immune system of the host and virulence factors of the parasite, equilibrating maximal …