Exercise is widely regarded as one of the most valuable components of behaviour that can
influence body weight and therefore help in the prevention and management of obesity …

Serotonin has been implicated in the control of satiety for almost four decades. Historically,
the insight that the appetite suppressant effect of fenfluramine is linked to serotonin has …

Obesity is a global epidemic that contributes to a number of health complications including
cardiovascular disease, type 2 diabetes, cancer and neuropsychiatric disorders …

Although weight loss can usually be achieved by restricting food intake, the majority of
dieters regain weight over the long-term. In the hypothalamus, hormonal signals from the …

Obesity is a growing health problem in our society and its treatment has been challenging. In
recent decades, several anti-obesity drugs have been withdrawn from the market because of …

Major depression is a debilitating and recurrent disorder with a substantial lifetime risk and a
high social cost. Depressed patients generally display co-morbid symptoms, and depression …

• The comorbidity of psychiatric diagnoses was examined with the Diagnostic Interview
Schedule in 62 women who participated in a 10-year follow-up study of anorexia nervosa …

Several areas in the brainstem and forebrain are important for the modulation and
expression of the sleep/wake cycle. Even if the first observations of biochemical events in …

Food intake is mediated, in part, through brain pathways for motivation and reinforcement.
Dysregulation of these pathways may underlay some of the behaviors exhibited by patients …

Background: We performed a retrospective analysis of 122 clinical records of 92 male
patients with DSM-III-R schizophrenia to examine the relative weight gain liabilities of …