Signaling pathways involved in colorectal cancer: Pathogenesis and targeted therapy

Q Li, S Geng, H Luo, W Wang, YQ Mo, Q Luo… - … and Targeted Therapy, 2024 - nature.com
Colorectal cancer (CRC) remains one of the leading causes of cancer-related mortality
worldwide. Its complexity is influenced by various signal transduction networks that govern …

The microbial landscape of colorectal cancer

MT White, CL Sears - Nature Reviews Microbiology, 2024 - nature.com
Colorectal cancer (CRC) is a substantial source of global morbidity and mortality in dire
need of improved prevention and treatment strategies. As our understanding of CRC grows …

Polysaccharide-based hydrogels and their application as drug delivery systems in cancer treatment: a review

M Dattilo, F Patitucci, S Prete, OI Parisi… - Journal of Functional …, 2023 - mdpi.com
Hydrogels are three-dimensional crosslinked structures with physicochemical properties
similar to the extracellular matrix (ECM). By changing the hydrogel's material type …

Healthy lifestyle and cancer risk: modifiable risk factors to prevent cancer

P Marino, M Mininni, G Deiana, G Marino, R Divella… - Nutrients, 2024 - mdpi.com
Cancer has become a serious problem worldwide, as it represents the main cause of death,
and its incidence has increased over the years. A potential strategy to counter the growing …

Curcumin suppresses colorectal cancer by induction of ferroptosis via regulation of p53 and solute carrier family 7 member 11/glutathione/glutathione peroxidase 4 …

T Ming, J Lei, Y Peng, M Wang, Y Liang… - Phytotherapy …, 2024 - Wiley Online Library
Driven by iron‐dependent lipid peroxidation, ferroptosis is regulated by p53 and solute
carrier family 7 member 11 (SLC7A11)/glutathione/glutathione peroxidase 4 (GPX4) axis in …

[HTML][HTML] Colorectal cancer: disease process, current treatment options, and future perspectives

AS Adebayo, K Agbaje, SK Adesina, O Olajubutu - Pharmaceutics, 2023 - mdpi.com
Colorectal cancer (CRC) is one of the deadliest malignancies in the US, ranking fourth after
lung, prostate, and breast cancers, respectively, in general populations. It continues to be a …

Recent advancements, limitations, and future perspectives of the use of personalized medicine in treatment of colon cancer

A Dey, A Mitra, S Pathak, S Prasad… - … in Cancer Research …, 2023 - journals.sagepub.com
Due to the heterogeneity of colon cancer, surgery, chemotherapy, and radiation are
ineffective in all cases. The genomic profile and biomarkers associated with the process are …

Herb and spices in colorectal cancer prevention and treatment: A narrative review

MS Hossain, MA Kader, KW Goh, M Islam… - Frontiers in …, 2022 - frontiersin.org
Colorectal cancer (CRC) is the second most deadly cancer worldwide. CRC management is
challenging due to late detection, high recurrence rate, and multi-drug resistance. Herbs and …

The role of curcumin in cancer: a focus on the PI3K/Akt pathway

V Zoi, AP Kyritsis, V Galani, D Lazari, C Sioka… - Cancers, 2024 - mdpi.com
Simple Summary Cancer has a major impact on societies across the world. In an attempt to
find new treatment options for cancer, attention has shifted to natural compounds. Curcumin …

The role of deep learning in diagnosing colorectal cancer

D Bousis, GI Verras, K Bouchagier… - Gastroenterology …, 2023 - termedia.pl
Colon cancer is a major public health issue, affecting a growing number of individuals
worldwide. Proper and early diagnosis of colon cancer is the necessary first step toward …