Cancer nanomedicines were initially envisioned as magic bullets, travelling through the
circulation to target tumours while sparing healthy tissues the toxicity of classic …

In recent years, nanoparticles have evolved to a clinical modality to deliver diverse nucleic
acids. Rising interest in nanomedicines comes from proven safety and efficacy profiles …

Induced tolerogenic dendritic cells are a powerful immunotherapy for autoimmune disease
that have shown promise in laboratory models of disease and early clinical trials. In contrast …

In the past few decades, biological drugs and small molecule inhibitors targeting
inflammatory cytokines, immune cells, and intracellular kinases have become the standard …

Although only a few stem cell-based therapies are currently available to patients, stem cells
hold tremendous regenerative potential, and several exciting clinical applications are on the …

The lymphatic system serves an integral role in fluid homeostasis, lipid metabolism and
immune control. In cancer, the lymph nodes that drain solid tumours are a primary site of …

The continued evolution of biomedical nanotechnology has enabled clinicians to better
detect, prevent, manage, and treat human disease. In order to further push the limits of …

Regulatory T cells hold promise as targets for therapeutic intervention in autoimmunity, but
approaches capable of expanding antigen-specific regulatory T cells in vivo are currently not …

Covalent organic frameworks (COFs) are porous organic polymeric materials that are
composed of organic elements and linked together by the thermodynamically stable …

Background & aims In celiac disease (CeD), gluten induces immune activation, leading to
enteropathy. TAK-101, gluten protein (gliadin) encapsulated in negatively charged poly (dl …