Advances in drug delivery systems, challenges and future directions
Advances in molecular pharmacology and an improved understanding of the mechanism of
most diseases have created the need to specifically target the cells involved in the initiation …
most diseases have created the need to specifically target the cells involved in the initiation …
Mesoporous silica materials: From physico-chemical properties to enhanced dissolution of poorly water-soluble drugs
A Maleki, H Kettiger, A Schoubben… - Journal of Controlled …, 2017 - Elsevier
New approaches in pharmaceutical chemistry have resulted in more complex drug
molecules in the quest to achieve higher affinity to their targets. However, these 'highly …
molecules in the quest to achieve higher affinity to their targets. However, these 'highly …
Self-microemulsifying drug delivery system (SMEDDS)–challenges and road ahead
S Dokania, AK Joshi - Drug delivery, 2015 - Taylor & Francis
Self-microemulsifying drug delivery system (SMEDDS) has emerged as a vital strategy to
formulate poor water soluble compounds for bioavailability enhancement. However, certain …
formulate poor water soluble compounds for bioavailability enhancement. However, certain …
Self-nanoemulsifying drug delivery system (SNEDDS) mediated improved oral bioavailability of thymoquinone: optimization, characterization, pharmacokinetic, and …
Thymoquinone (TQ) is an antioxidant, anti-inflammatory, and hepatoprotective compound
obtained from the black seed oil of Nigella sativa. However, high hydrophobicity, instability …
obtained from the black seed oil of Nigella sativa. However, high hydrophobicity, instability …
Quercetin-containing self-nanoemulsifying drug delivery system for improving oral bioavailability
Quercetin is a dietary flavonoid with potential chemoprotective effects, but has low
bioavailability because of poor aqueous solubility and low intestinal absorption. A quercetin …
bioavailability because of poor aqueous solubility and low intestinal absorption. A quercetin …
Self-nanoemulsifying drug delivery system (SNEDDS) with enhanced solubilization of nystatin for treatment of oral candidiasis: Design, optimization, in vitro and in …
The aim of the present study is to develop and optimize self-nanoemulsifying drug delivery
systems (SNEDDSs) to improve the per-oral bioavailability of poorly soluble polyene …
systems (SNEDDSs) to improve the per-oral bioavailability of poorly soluble polyene …
Optimized self nano-emulsifying systems of ezetimibe with enhanced bioavailability potential using long chain and medium chain triglycerides
The objective of the current work is to develop systematically optimized self-nanoemulsifying
drug delivery systems (SNEDDS) using long chain triglycerides (LCT's) and medium chain …
drug delivery systems (SNEDDS) using long chain triglycerides (LCT's) and medium chain …
Improved pharmacodynamic potential of rosuvastatin by self-nanoemulsifying drug delivery system: An in vitro and in vivo evaluation
Purpose The purpose of this proposed research was to investigate a nano-formulation
developed using self-nanoemulsifying drug delivery system (SNEDDS) to improve the …
developed using self-nanoemulsifying drug delivery system (SNEDDS) to improve the …
Nanoemulsion liquid preconcentrates for raloxifene hydrochloride: optimization and in vivo appraisal
Raloxifene hydrochloride (RLX) is a selective estrogen-receptor modulator for treatment of
osteoporosis and prevention of breast and endometrial cancer. By virtue of extensive …
osteoporosis and prevention of breast and endometrial cancer. By virtue of extensive …
Novel Self-Nano Emulsifying Drug Delivery System (SNEDDS) of andrographolide isolated from Andrographis paniculata Nees: Characterization, in-vitro and in-vivo …
This study aimed to conduct a preparation and characterization of andrographolide isolated
from Andrographis paniculata Nees (AND)-loaded Self-Nano Emulsifying Drug Delivery …
from Andrographis paniculata Nees (AND)-loaded Self-Nano Emulsifying Drug Delivery …