Adipose tissue inflammation and metabolic dysfunction in obesity

T Kawai, MV Autieri, R Scalia - American Journal of …, 2021 - journals.physiology.org
Several lines of preclinical and clinical research have confirmed that chronic low-grade
inflammation of adipose tissue is mechanistically linked to metabolic disease and organ …

The circadian clock, shift work, and tissue-specific insulin resistance

JE Oosterman, S Wopereis, A Kalsbeek - Endocrinology, 2020 - academic.oup.com
Obesity and type 2 diabetes (T2D) have become a global health concern. The prevalence of
obesity and T2D is significantly higher in shift workers compared to people working regular …

[HTML][HTML] Cardiometabolic health improvements upon dietary intervention are driven by tissue-specific insulin resistance phenotype: a precision nutrition trial

I Trouwborst, A Gijbels, KM Jardon, E Siebelink, GB Hul… - Cell Metabolism, 2023 - cell.com
Precision nutrition based on metabolic phenotype may increase the effectiveness of
interventions. In this proof-of-concept study, we investigated the effect of modulating dietary …

[HTML][HTML] Tissue-specific inflammation and insulin sensitivity in subjects with obesity

SM Oussaada, M Kilicarslan, BA de Weijer… - Diabetes Research and …, 2024 - Elsevier
Obesity is associated with low-grade inflammation and insulin resistance (IR). The
contribution of adipose tissue (AT) and hepatic inflammation to IR remains unclear. We …

Adipose tissue immunomodulation: a novel therapeutic approach in cardiovascular and metabolic diseases

I AlZaim, SH Hammoud, H Al-Koussa… - Frontiers in …, 2020 - frontiersin.org
Adipose tissue is a critical regulator of systemic metabolism and bodily homeostasis as it
secretes a myriad of adipokines, including inflammatory and anti-inflammatory cytokines. As …

Metabolic phenoty** in people living with obesity: implications for dietary prevention

EE Blaak, GH Goossens - Reviews in Endocrine and Metabolic Disorders, 2023 - Springer
Given the increasing number of people living with obesity and related chronic metabolic
disease, precision nutrition approaches are required to increase the effectiveness of …

Chronic stress, epigenetics, and adipose tissue metabolism in the obese state

Y ** review
H Hornero-Ramirez, A Aubin, MC Michalski… - Frontiers in …, 2024 - frontiersin.org
Background Growing evidence highlights the significant impact of diet to modify low-grade
inflammation closely linked to cardiometabolic profile. Multifunctionnal diets, combining …