Clinical and epidemiological studies support a connection between obesity and thrombosis,
involving elevated expression of the prothrombotic molecules plasminogen activator …

Simple Summary As overweight and obesity increase among the population worldwide, a
parallel increase in the number of individuals diagnosed with prostate cancer was observed …

Coagulation and fibrinolytic activities are under strong genetic control. We studied the effects
of acquired obesity, independent of genetic factors on coagulation and fibrinolysis activities …

Obesity is a prevalent prothrombotic risk factor marked by enhanced fibrin formation and
suppressed fibrinolysis. Fibrin both promotes thrombotic events and drives obesity …

Objective: Obesity is characterized by chronic low-grade inflammation and consequentially a
hypercoagulable state, associating with an increased incidence of venous …

Numerous studies on various animal species, with variability in the site of application and
the concentration of ferric chloride (FeCl3) to induce intravascular thrombosis has prompted …

Abstract Factor XIII-A (FXIII-A) transglutaminase (TG) was recently identified as a potential
causative obesity gene in human white adipose tissue (WAT). Here, we have examined the …

Obesity is a common disorder and a known risk factor for thrombotic complications.
Development of obesity is associated with extensive modifications in adipose tissue …

Obesity is a major risk factor for cardiovascular disease. An increased body mass index
(BMI) is associated with venous thromboembolism, myocardial infarction, stroke and stent …

Hepatocyte nuclear factor 4α (HNF4α) and CCAAT/enhancer-binding protein α (C/EBPα) are
important for the transcriptional control of coagulation factors. To determine in vivo the direct …