The alphabet of building blocks for RNA molecules is much larger than the standard four
nucleotides. The diversity is achieved by the post-transcriptional biochemical modification of …

RNAs are central to protein synthesis, with ribosomal RNA, transfer RNAs and messenger
RNAs comprising the core components of the translation machinery. In addition to the four …

Queuosine (Q) is a conserved tRNA modification at the wobble anticodon position of tRNAs
that read the codons of amino acids Tyr, His, Asn, and Asp. Q-modification in tRNA plays …

Inosine is one of the most common post-transcriptional modifications. Since its discovery, it
has been noted for its ability to contribute to non-Watson-Crick interactions within RNA …

Transfer RNAs (tRNAs) are essential adaptors that mediate translation of the genetic code.
These molecules undergo a variety of post-transcriptional modifications, which expand their …

Cellular tRNAs appear today as a diverse population of informative macromolecules with
conserved general elements ensuring essential common functions and different and …

Transfer RNA (tRNA) is the most diversely modified RNA. Although the strictly conserved
purine position 37 in the anticodon stem–loop undergoes modifications that are …

Transfer RNA (tRNA) modifications play a crucial role in maintaining translational fidelity and
efficiency, and they may function as regulatory elements in stress response and virulence …

Ribonucleic acids (RNAs) play a vital role in living organisms. Many of their cellular
functions depend critically on chemical modification. Methods to modify RNA in a controlled …

Post-transcriptional modifications are crucial for RNA function, with roles ranging from the
stabilization of functional RNA structures to modulation of RNA–protein interactions …