Nanoparticles‐induced potential toxicity on human health: applications, toxicity mechanisms, and evaluation models

L Xuan, Z Ju, M Skonieczna, PK Zhou, R Huang - MedComm, 2023 - Wiley Online Library
Nanoparticles (NPs) have become one of the most popular objects of scientific study during
the past decades. However, despite wealth of study reports, still there is a gap, particularly in …

Nanoparticles in cancer diagnosis and treatment

J Baranwal, B Barse, A Di Petrillo, G Gatto, L Pilia… - Materials, 2023 - mdpi.com
The use of tailored medication delivery in cancer treatment has the potential to increase
efficacy while decreasing unfavourable side effects. For researchers looking to improve …

[HTML][HTML] Different types of cell death in diabetic endothelial dysfunction

J Shen, W San, Y Zheng, S Zhang, D Cao… - Biomedicine & …, 2023 - Elsevier
Diabetes mellitus is a metabolic disease caused by disorders of insulin secretion and
utilization. Long-term hyperglycemia, insulin resistance, and disorders of glucose and lipid …

Copper-containing bioactive glasses and glass-ceramics: From tissue regeneration to cancer therapeutic strategies

S Kargozar, M Mozafari, S Ghodrat, E Fiume… - Materials Science and …, 2021 - Elsevier
Copper is one of the most used therapeutic metallic elements in biomedicine, ranging from
antibacterial approaches to cancer theranostics. This element could be easily incorporated …

The molecular mechanisms of defective copper metabolism in diabetic cardiomyopathy

X Cui, Y Wang, H Liu, M Shi, J Wang… - Oxidative Medicine and …, 2022 - Wiley Online Library
Copper is an essential trace metal element that significantly affects human physiology and
pathology by regulating various important biological processes, including mitochondrial …

Copper homeostasis and cuproptosis in cancer immunity and therapy

WQ Liu, WR Lin, L Yan, WH Xu… - Immunological Reviews, 2024 - Wiley Online Library
Copper is an essential nutrient for maintaining enzyme activity and transcription factor
function. Excess copper results in the aggregation of lipoylated dihydrolipoamide S …

Biogenic synthesis of Cu-Mn bimetallic nanoparticles using pumpkin seeds extract and their characterization and anticancer efficacy

NO Alafaleq, TA Zughaibi, NR Jabir, AU Khan… - Nanomaterials, 2023 - mdpi.com
Background: Cancer is a chronic, heterogeneous illness that progresses through a spectrum
of devastating clinical manifestations and remains the 2nd leading contributor to global …

Copper oxide nanoparticles stimulate the immune response and decrease antioxidant defense in mice after six-week inhalation

J Tulinska, ML Mikusova, A Liskova, M Busova… - Frontiers in …, 2022 - frontiersin.org
Copper oxide nanoparticles (CuO NPs) are increasingly used in various industry sectors.
Moreover, medical application of CuO NPs as antimicrobials also contributes to human …

Copper and Zinc Particles as Regulators of Cardiovascular System Function—A Review

K Kitala, D Tanski, J Godlewski… - Nutrients, 2023 - mdpi.com
Copper and zinc are micronutrients that play a crucial role in many cellular pathways, act as
cofactors in enzymatic systems, and hence, modulate enzyme activity. The regulation of …

PINK1/TAX1BP1-directed mitophagy attenuates vascular endothelial injury induced by copper oxide nanoparticles

Y Fan, Z Cheng, L Mao, G Xu, N Li, M Zhang… - Journal of …, 2022 - Springer
Copper oxide nanoparticles (CuONPs) are widely used metal oxide NPs owing to their
excellent physical–chemical properties. Circulation translocation of CuONPs after inhalation …